ID   A0A3Q0CP92_MESAU        Unreviewed;       531 AA.
AC   A0A3Q0CP92;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=4F2 cell-surface antigen heavy chain isoform X1 {ECO:0000313|RefSeq:XP_021081809.1};
GN   Name=Slc3a2 {ECO:0000313|RefSeq:XP_021081809.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021081809.1};
RN   [1] {ECO:0000313|RefSeq:XP_021081809.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=26319212;
RA   Ying B., Toth K., Spencer J.F., Aurora R., Wold W.S.;
RT   "Transcriptome sequencing and development of an expression microarray
RT   platform for liver infection in adenovirus type 5-infected Syrian golden
RT   hamsters.";
RL   Virology 485:305-312(2015).
RN   [2] {ECO:0000313|RefSeq:XP_021081809.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_021081809.1; XM_021226150.1.
DR   AlphaFoldDB; A0A3Q0CP92; -.
DR   STRING; 10036.ENSMAUP00000012869; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR042280; SLC3A2.
DR   InterPro; IPR031984; SLC3A2_N.
DR   PANTHER; PTHR46673; 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN; 1.
DR   PANTHER; PTHR46673:SF1; 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   Pfam; PF16028; SLC3A2_N; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          123..424
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   531 AA;  58259 MW;  6354F7531A47F067 CRC64;
     MSQDTEVDMK EVELNELEPE KQPMNAAAGA AAGEKNGLVK IKVAEDGAEA GAKFTGLSKE
     ELLKVAGSPG WVRTRWALLL LFWLGWLGML AGAVVIIVRA PRCRELPVQR WWHEGALYRV
     GDLQAFVGPN AGGIAGLKKH LEYLSTLKVK GLVLGPVHKN QKDEVNGTDL KQIDPTLGSQ
     EDFKDFLQSA KKKSIHIILD LTPNYRGQNA WFLPAQADIV ATKMKEALSS WLQDGVDGFQ
     VRDVEKLMDA SLYLAEWQNI TKNFSEDRLL IAGTDSSNLQ QIVSILESTG DLLLTSSYLS
     NSSFTGEHTE LLVTRYLNAT GSHWCSWSVS QAGLLTASVP AQLLRLYQLM LFTLPGTPVF
     SYGDEIGLQA AVLPGQPVEA PFMPWDESSL PQSPGHISAN MTVKGQSEDP SSLLTQFQWL
     SGLRGKERGK ERSLLHGDFH VLTSSSGIFS YIRYWDQNER YLVVLNFQDV GLSARLGASN
     LPAGISLPAS AKLLFSTNST RLGQEEGTSL SLENLNLNPH EGLLLHFPYV A
//