ID A0A3Q0CTR7_MESAU Unreviewed; 1042 AA.
AC A0A3Q0CTR7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=LOW QUALITY PROTEIN: FERM domain-containing protein 4B {ECO:0000313|RefSeq:XP_021083484.1};
GN Name=Frmd4b {ECO:0000313|RefSeq:XP_021083484.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021083484.1};
RN [1] {ECO:0000313|RefSeq:XP_021083484.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26319212;
RA Ying B., Toth K., Spencer J.F., Aurora R., Wold W.S.;
RT "Transcriptome sequencing and development of an expression microarray
RT platform for liver infection in adenovirus type 5-infected Syrian golden
RT hamsters.";
RL Virology 485:305-312(2015).
RN [2] {ECO:0000313|RefSeq:XP_021083484.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_021083484.1; XM_021227825.1.
DR STRING; 10036.ENSMAUP00000005289; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR CDD; cd17200; FERM_F1_FRMD4B; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR021774; CUPID.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047176; FRMD4A/B.
DR InterPro; IPR041785; FRMD4A/B_FERM_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46079:SF1; FERM DOMAIN-CONTAINING PROTEIN 4B; 1.
DR Pfam; PF11819; CUPID; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 59..361
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 576..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 999..1042
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 916..933
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 999..1024
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1042 AA; 118875 MW; 4D9514346062F7BC CRC64;
MASVFMCGVE DLLFSGSRFV WNLTVSTLRR WYTERLRACH QVLRSWCGLR DVYQMTEGRH
CQVHLLDDRR LELLVQPKLL SRELLDLVAS HFNLKEKEYF GITFIDDTGQ ENWLQLDHRV
LEHDLPKKPG PATLHFAVRF YIESISFLKD KNTVELFFLN AKACVHKGQI EVDSETIFKL
AALVLQESKG DYTSDENARK DLKTLPVFPT KTLQEHPSLA YCEDRVIEHY LKIKGLTRGQ
AVVQYMKIVE ALPTYGVHYY AVKDKQGLPW WLGISYKGIG QYDLQDKVKP RKLFQWKQLE
NLYFREKKFA VEVHDPRRIS VSRRTFGQSG LFVQTWYANS SLIKSIWVMA ISQHQFYLDR
KQSKAKIPSA RSLDDIAMDL TETGAQRVSK LVTLEAKSQF IMASNGSLIS SGSQDSEGME
EQKREKILEL KKKEKLLQEK LLKKVEELKK ICLREAELTG RMPKEYPLSI GEKPPQVRRR
VGTTFKLDDN LLPTEEDPAL QELESNFLIQ QKLVEAAKKL ASEPDLCKTV KKKRKQDYTD
AVKRLQEIEN SINEYRIRCG KKPSQKTTVV LPEDIIPSES SSLSDTTTYD DPNDSFTLAG
QRPSSVPHSP RILPPKSLGI ERIHFRKSSI NDQFMDTRQS REMLSTHSSP YKTLERRPQG
GRSMPTTPVL TRNAYSSSHL EXELPFCCFN PDSSTQHCRQ RSGSLESQSH LLSEMDSDKP
FFTLSKSQRS SSTEILDDGS SYTSQSSSEY YCVTPASGPY YTTQTLDTRA RGRRRSKKQN
VSTSNSGSMP NLAQKDTLRN GVYSKGQDPS GYYIAGYTPY AECDLYYSGG YVYENDTEGQ
YSVNPSYRSS AHYGYDRQRD YSRSFHEDEV DRVPHNPYAT LRLPRKAAVK SEHITKNIHK
ALVAEHLRGW YQRASGQKDQ GHSPQTSFDS DRGSQRCLGF PGLQVPCSPS SRASSYSSVS
STNASGNWRT QLTVGLSEYE NPVHSPYTSC YGSIYNPLPS PSRQYAETTP LDGTDGNQLE
DNLESGEQRL FWHEDSKPGT LV
//
