ID A0A3Q0CXH8_MESAU Unreviewed; 1137 AA.
AC A0A3Q0CXH8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=NFX1-type zinc finger-containing protein 1 isoform X2 {ECO:0000313|RefSeq:XP_021085393.1};
GN Name=Znfx1 {ECO:0000313|RefSeq:XP_021085393.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021085393.1};
RN [1] {ECO:0000313|RefSeq:XP_021085393.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_021085393.1; XM_021229734.1.
DR AlphaFoldDB; A0A3Q0CXH8; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd17936; EEXXEc_NFX1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR046439; ZF_RZ_dom.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF20173; ZnF_RZ-type; 1.
DR SMART; SM00438; ZnF_NFX; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51981; ZF_RZ; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1046..1117
FT /note="RZ-type"
FT /evidence="ECO:0000259|PROSITE:PS51981"
FT REGION 12..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..42
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1137 AA; 129896 MW; 3C5341FD865FB22E CRC64;
MMLEWLGLGV GTFTQSASPA GPESTAQAEG EEEEEGEEEG SLIEIAEEAD LIQADRVIEE
EEVVRPRRRK KEENAVDQEL AKMLLAMRLD QYGPVTTAGQ EQATEEWEIQ HNQRRKMKRK
VKVELLKLNT MTEAEASAIQ DIWQLDLSTR WQLYRLWLQM YQADTWRKIL SYERQYRTSA
ERMAELRLQE DLHILKDAQI VGMTTTGAAK YRQILQQVEP RIVIVEEAAE VLEAHTIATL
SKACQHLILI GDHQQLRPSA NVYDLAKNFN LEVSLFERLV KVNIPFVRLN HQHRMRPEIA
RLLTPHIYQD LENHPSVLKY EQIKGVSSNL FFVEHNFPEQ DIQEGKSHQN QHEAHFVVEL
CQYFLCQEYL PSQITILTTY TGQLFCLRKL MPAKTFAGIK VHVVDKYQGE ENDIILLSLV
RSNPEGKVGF LQIPNRICVA LSRAKKGMYC IGNMQMLARV PLWSKIIHTL RENNQIGSSL
RLCCQNHPDT HTLVSKASDF QKVPEGGCSL PCEFRLACGH VCTRACHPYD SSHREFQCMK
PCQKVICPDG HRCPLVCFQE CQSCQVKVPK IVLRCGHQQM VPCSVPESDF CCQEPCPKVL
RCGHRCSNLC GEDCVRLCSE KVTVKLKCGH SQQVKCGNVE DVKYGLSVKC TTKCDTILDC
GHPCPGSCHS CFEGRFHERC QQPCKRLLIC SHKCQEPCIG KCPPCQRTCQ NRCVHSQCKK
KCGELCSPCV EPCVWRCQHY QCTKLCSEPC NRPPCYVPCT KLLACGHPCI GLCGEPCPKK
CRVCQLDEVT QIFFGFEDEP DARFVQLEEC SHIFEVQALD RYMNEQKDDE VAIRLKVCPI
CQVPIRKNLR YGTSIKQRLE EIEIVKEKIQ GSSREIAASQ EQLKALLKSK ALFFQVRPEE
FLMLEEKLAQ KNLSVKDLGL VENSISFYDH LANLEGSLKK VHYLERQRVR TRLEQVYEWL
AKKRLSFSSQ ELSDLQSEIQ RLTYLVNLLM RCKMAKEKVK GSVAEEVSSI RNILEKTCKF
TQEDEQLVQK KMDALKTTLP CSGLGISEEE RVQIVTALGV PRGHWFKCPN GHIYVITECG
GAMQRGTCPE CQEVIGGENH TLERSNQLAP EMDGAQHPAW SDTANNLMNF EEIHRMI
//
