ID A0A3Q0CXY4_MESAU Unreviewed; 560 AA.
AC A0A3Q0CXY4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Interferon alpha/beta receptor 1 {ECO:0000313|RefSeq:XP_021085114.1};
GN Name=Ifnar1 {ECO:0000313|RefSeq:XP_021085114.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021085114.1};
RN [1] {ECO:0000313|RefSeq:XP_021085114.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28071753;
RA McCann K.E., Sinkiewicz D.M., Norvelle A., Huhman K.L.;
RT "De novo assembly, annotation, and characterization of the whole brain
RT transcriptome of male and female Syrian hamsters.";
RL Sci. Rep. 7:40472-40472(2017).
RN [2] {ECO:0000313|RefSeq:XP_021085114.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC Lysosome {ECO:0000256|ARBA:ARBA00004371}.
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DR RefSeq; XP_021085114.1; XM_021229455.1.
DR AlphaFoldDB; A0A3Q0CXY4; -.
DR STRING; 10036.ENSMAUP00000014164; -.
DR OrthoDB; 5320327at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859:SF54; INTERFERON ALPHA_BETA RECEPTOR 1; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF09294; Interfer-bind; 2.
DR Pfam; PF01108; Tissue_fac; 1.
DR SMART; SM00060; FN3; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR PROSITE; PS50853; FN3; 2.
PE 4: Predicted;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Receptor {ECO:0000313|RefSeq:XP_021085114.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Signal {ECO:0000256|SAM:SignalP};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..560
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018205263"
FT DOMAIN 31..126
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 332..427
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 507..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 518..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 62683 MW; 4C5533E040BEA378 CRC64;
MLGLLGSAAL VLVAGAPWVL LAAADGEELE PPEDVDVYIV DDNLTLKWSH KGEPAGNVTF
SAEYQTDEME NWLKLPGCHH VTGTECEFSL LNTNIYAEMK FRVRAETGKS TSSWAEVDPF
IPFLRAHIGP PGVRLEAEDQ AIVVDISYPG RGGKMWEGDT LRFQYRIVIW QRSSNETKTI
TTSYYTIKIS KLLPETTYCL KVKAIHTFRG KHSNYSAVQC INTTEASKMP VPENIEMDAL
GESYVLRWDC APADVSFRAQ WLPNFYKSTS GSSPDKWKPI PACADIRTMQ CVFPRNTIHT
DHFLLRVQAF RGNNTSFWSE EKLINSQKYT KIPPPIVAVT PTRDSLLVYV SCQDHSLSKC
RKLTYEVVFW DKTSNTKRRV VKESPEFTIE NLQPQTVYCV QARVLSFATW NKSSDFSDAL
CDATRPGNSS SMNWILTVLG TLFFSALALY AGKNLVKCLN SEFFSSPKPP PSIDEVFSEP
PSKYLLFLTP EEHTERCFII ENTGTVAVTG GNPSPEGEHR KYTSQSSQDS GNYSNEEEST
GSENSQGLRP QGCPEHSGPF
//
