ID A0A3Q0D0P2_MESAU Unreviewed; 989 AA.
AC A0A3Q0D0P2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Multiple epidermal growth factor-like domains protein 11 isoform X6 {ECO:0000313|RefSeq:XP_021086049.1};
GN Name=Megf11 {ECO:0000313|RefSeq:XP_021086049.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021086049.1};
RN [1] {ECO:0000313|RefSeq:XP_021086049.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_021086049.1; XM_021230390.1.
DR AlphaFoldDB; A0A3Q0D0P2; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 2.
DR Gene3D; 2.10.25.140; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 5.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF7; MULTIPLE EGF LIKE DOMAINS 11; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF12661; hEGF; 5.
DR Pfam; PF00053; Laminin_EGF; 8.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 17.
DR SMART; SM00180; EGF_Lam; 16.
DR PROSITE; PS00022; EGF_1; 14.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 11.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..989
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017991175"
FT TRANSMEM 849..871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..101
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 143..173
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 181..216
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 224..259
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 267..302
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 310..345
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 442..477
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 485..520
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 571..606
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 659..694
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 750..780
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 753..794
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 788..823
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 163..172
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 206..215
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 249..258
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 292..301
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 335..344
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 467..476
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 510..519
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 596..605
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 684..693
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 770..779
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 813..822
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 989 AA; 104754 MW; 4BEDAF304206324F CRC64;
MAPSTVGLLV VSLLQAALTL NPEDPNVCSH WESYAVTVQE SYAHPFDQIY YTRCADILNW
FKCTRHRISY KTAYRRGLRT MYRRRSQCCP GYYENGDFCI PLCTEECMHG RCVSPDTCHC
EPGWGGPDCS SGCDSEHWGP HCSNRCQCQN GALCNPITGA CVCAPGFRGW RCEELCAPGT
HGKGCQLPCQ CHHGASCDPR TGECLCAPGY TGVYCEELCP PGSHGAHCEL RCPCQNGGTC
HHITGECACP PGWMGAVCAQ PCPPGTFGQN CSQDCPCHHG GQCDHVTGQC HCTAGYMGDR
CQEECPFGTF GFRCSQRCDC RNGGQCSPTT GACECEPGYK GPSCRERLCP EGLHGPGCTL
PCPCDTENTI SCHPVTGACT CQPGWSGHFC NESCPAGYYG NGCQLPCTCQ NGADCHSITG
GCTCAPGFMG EVCAVPCASG TYGPNCSSVC SCSNGGTCSP VDGSCTCQEG WQGPDCSLPC
PSGTWGLNCN ETCVCANGAA CSPSDGSCDC TPGWLGDSCE LPCPDGTFGL NCSEHCDCSH
ADGCDPVTGH CCCLAGWTGI RCDSTCPPGR WGPNCSVSCS CENGGSCSPE DGSCECAPGF
RGPLCQRICP PGFYGHGCAQ SCPLCVHSSG PCHHVSGICE CLPGFSGALC NQVCAGGHFG
QDCAQLCSCA NNGTCSPIDG SCQCFPGWIG KDCSQACPSG FWGSACFHTC SCHNGASCSA
EDGACHCTPG WTGLFCTQRC PAAFFGKDCG HICQCQNGAS CDHITGKCTC RTGFTGRHCE
QRCAPGTFGY GCQQLCECMN NATCDHVTGT CYCSPGFKGI RCDQAALMMD ELNPYTKISP
ALGAERHSVG AVTGIILLLF LVVVLLGLYA WRRRRQKEKG RDLAPRVSYT PAMRMTSTDY
SLSDLSQSSS HAQCFSNTSY HTLACGVPAT SQASTLDRNS PTKARVEWID VRTHTLWTKA
SKRPSVVLAR ITTLNMLPFW CTRNGKDAQ
//
