ID A0A3Q0D1W1_MESAU Unreviewed; 587 AA.
AC A0A3Q0D1W1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Ankyrin repeat and SOCS box protein 14 {ECO:0000313|RefSeq:XP_021087242.1};
GN Name=Asb14 {ECO:0000313|RefSeq:XP_021087242.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021087242.1};
RN [1] {ECO:0000313|RefSeq:XP_021087242.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR RefSeq; XP_012974232.1; XM_013118778.1.
DR RefSeq; XP_021087242.1; XM_021231583.1.
DR AlphaFoldDB; A0A3Q0D1W1; -.
DR STRING; 10036.ENSMAUP00000003758; -.
DR KEGG; maua:101835001; -.
DR OrthoDB; 5479200at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03730; SOCS_ASB14; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24188:SF29; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24188; ANKYRIN REPEAT PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 7.
DR PROSITE; PS50088; ANK_REPEAT; 8.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT REPEAT 116..148
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 149..181
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 182..214
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 215..247
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 248..280
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 313..345
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 355..380
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 385..417
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 529..576
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 587 AA; 65242 MW; 5BF179599158008B CRC64;
MDNSNSDEDT DTDFETQLII QQSLLDIYKP GITQHTSEDK RSHSVLSADH KKIIEAIEAG
KEDALAHLTR CQSAFDEANG DGWLPLHKAA VHLNRNILEI TLKASKPSAW EHTTHNGETP
LFLAVSSSLL ENVHFLLLNG CNPDAKNLEG NSPLLTAVLK DSYDMATLLI SHGADVNLRC
ANERTALHEA AKLGRLDMVK LMLASGAHPD ARSSYGFTPL ALAAQSGHTE IMELLLQKGA
DAHSQASDCS SILLEAVRGG NPDSVTLLLE NGADANIPKS SGHLPIHVAA DKGHLLALKM
LVPVTDIAAI KRSGISPIHC AAAGAHPQCL ELLIQAGFDV NFMLDQRIRK YYDDQRKSAL
YFAVSNGDLS SVKLLLSAGA LPNQDPVNCL QIALRMGNYE LISLLLRHGA NVNYFCRVNP
LHFPSALQYS LKDEVMLRML LNYGYDTERC FDCPHGDRVH RLCTFEGWTS TVIKDTMFCE
VITLSWLQHL SGKVVRVMLD YVDQVQICSK LKAVLEKQKL WSEIHFILTN PRSLKHLCRL
KIRKCMGRLR LRCPVFMSFL PLPKRLKAYV LYEEYNLYGQ ESFTGSW
//
