ID   A0A3Q0D5A7_MESAU        Unreviewed;      1036 AA.
AC   A0A3Q0D5A7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Inversin isoform X3 {ECO:0000313|RefSeq:XP_021087931.1};
GN   Name=Invs {ECO:0000313|RefSeq:XP_021087931.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021087931.1};
RN   [1] {ECO:0000313|RefSeq:XP_021087931.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
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DR   RefSeq; XP_021087931.1; XM_021232272.1.
DR   AlphaFoldDB; A0A3Q0D5A7; -.
DR   Proteomes; UP000189706; Unplaced.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   PANTHER; PTHR24178:SF2; INVERSIN; 1.
DR   PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR   Pfam; PF00023; Ank; 2.
DR   Pfam; PF12796; Ank_2; 5.
DR   Pfam; PF00612; IQ; 2.
DR   SMART; SM00248; ANK; 15.
DR   SMART; SM00015; IQ; 2.
DR   SUPFAM; SSF48403; Ankyrin repeat; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 10.
DR   PROSITE; PS50088; ANK_REPEAT; 11.
DR   PROSITE; PS50096; IQ; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT   REPEAT          47..79
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          80..112
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          148..180
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          220..240
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          254..286
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          288..320
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          356..388
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          389..421
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          422..454
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          455..487
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          495..527
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          596..838
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        596..617
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        660..686
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..744
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        775..789
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1036 AA;  114870 MW;  30CC9CE3CB6416B9 CRC64;
     MNISENVLSS GSSLASQVHA AAVNGDKGAL QRLIVGNPSL KDKEDQFGRT PLMYCVLADR
     LDCADALLKA GADVNKTDHS RRTALHLAAQ KGNYRFMKLL LTRRANWMQK DLEEMTPLHL
     TTRHKSPKCL ALLLKFMAPG EVDTQDKNKQ TALHWSAYYN NPEHAKLLIK HDSNIGIPDT
     EGKIPLHWAA NHKDPSAVHT VRCILEAAPT ESLLNWQDYE GRTPLHFAVA DGNLTVVDIL
     TSYESCNITS YDNLFRTPLH WAALLGHAQI VHLLLERNKS GTIPSDSQGA TPLHYAAQSN
     FAETVKVFLK HPSVKDDSDL EGRTSFMWAA GKGSDDVLRT MLSLKSDIDI NMADKYGGTA
     LHAAALSGHV STVKLLLDND AQVDATDVMK HTPLFRACEM GHKDVIQTLI KGGARVDLVD
     QDGHSLLHWA ALGGNADVCQ ILIENKINPN VQDYAGRTPL QCAAYGGYIT CMAVLMENNA
     DPNIQDKELI CSYLQGRTAL HWSCNNGYLD AIKLLLDFAA FPNQMETNEE RYTPLDYALL
     GERHEVIQFM LEHGALSIAA IQDIAAFKIQ AVYKGYKVRK AFRDRKNLLM KHEQLRKDAA
     AKKREEENKR KEAEQQKGQL STDTPRPQCL PCPPSPQNEP SKQSADPCKQ PPAGHTVQGP
     DPEHSRRSPG RRPGRASHRD CPSDLQETAS RKPSETPSEP CRRPSACVPV RACEGGDGCR
     HRGASSVEKC RGETNGKHQC EEGPSRARQP LSFGSAHPAE RGEDSSPASA SQQDSPRKPR
     RRQDRAPRPG GASQKRCVHQ LRDRCSPAGS SRPGSARGDL ACAEQSPLHH RTPRTKVTQH
     KLIGGVSSDL PPSTEELRSG CKMLCADVRA STESDVVHSP PPGQTVNIHL LPVEQRLQII
     QRERTRKELF RRKNKAAAVI QRAWRRYQLR KHLSRLLHVK QLGAGDVLRR SRVCTALLLQ
     VWRTQEELKF PKSISVSRVP KSSPKGMLAT KSARHSVLRR IYVNSLQSIH LDNSARSKKF
     SYNLQPASQS KSKPKL
//