ID A0A3Q0D8S5_MESAU Unreviewed; 2231 AA.
AC A0A3Q0D8S5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Neurogenic locus notch homolog protein 1 {ECO:0000256|ARBA:ARBA00019142};
GN Name=Notch1 {ECO:0000313|RefSeq:XP_021090735.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021090735.1};
RN [1] {ECO:0000313|RefSeq:XP_021090735.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NOTCH family.
CC {ECO:0000256|ARBA:ARBA00005847}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_021090735.1; XM_021235076.1.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0050793; P:regulation of developmental process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 26.
DR CDD; cd21702; JMTM_Notch1; 1.
DR Gene3D; 3.30.300.320; -; 1.
DR Gene3D; 3.30.70.3310; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.10.25.10; Laminin; 29.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR008297; Notch.
DR InterPro; IPR035993; Notch-like_dom_sf.
DR InterPro; IPR022362; Notch_1.
DR InterPro; IPR024600; Notch_C.
DR InterPro; IPR000800; Notch_dom.
DR InterPro; IPR010660; Notch_NOD_dom.
DR InterPro; IPR011656; Notch_NODP_dom.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00008; EGF; 14.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF12661; hEGF; 7.
DR Pfam; PF06816; NOD; 1.
DR Pfam; PF07684; NODP; 1.
DR Pfam; PF00066; Notch; 3.
DR PIRSF; PIRSF002279; Notch; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR PRINTS; PR01452; LNOTCHREPEAT.
DR PRINTS; PR01983; NOTCH.
DR PRINTS; PR01984; NOTCH1.
DR SMART; SM00248; ANK; 6.
DR SMART; SM01334; DUF3454; 1.
DR SMART; SM00181; EGF; 29.
DR SMART; SM00179; EGF_CA; 27.
DR SMART; SM00004; NL; 3.
DR SMART; SM01338; NOD; 1.
DR SMART; SM01339; NODP; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 12.
DR SUPFAM; SSF57184; Growth factor receptor domain; 5.
DR SUPFAM; SSF90193; Notch domain; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS00010; ASX_HYDROXYL; 20.
DR PROSITE; PS00022; EGF_1; 28.
DR PROSITE; PS01186; EGF_2; 23.
DR PROSITE; PS50026; EGF_3; 29.
DR PROSITE; PS01187; EGF_CA; 7.
DR PROSITE; PS50258; LNR; 3.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Angiogenesis {ECO:0000256|ARBA:ARBA00022657};
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Calcium {ECO:0000256|PIRSR:PIRSR002279-1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR002279-2};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR002279-1};
KW Notch signaling pathway {ECO:0000256|ARBA:ARBA00022976};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..32
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 34..70
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 71..109
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 111..149
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 151..187
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 189..225
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 227..263
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 265..300
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 302..338
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 340..375
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 377..413
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 415..450
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 452..488
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 490..526
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 528..566
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 568..604
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 606..642
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 644..680
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 682..718
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 720..756
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 758..794
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 807..842
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 844..880
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 882..918
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 927..964
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 966..1004
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1006..1045
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1047..1083
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1086..1125
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1148..1188
FT /note="LNR"
FT /evidence="ECO:0000259|PROSITE:PS50258"
FT DOMAIN 1189..1230
FT /note="LNR"
FT /evidence="ECO:0000259|PROSITE:PS50258"
FT DOMAIN 1231..1270
FT /note="LNR"
FT /evidence="ECO:0000259|PROSITE:PS50258"
FT REPEAT 1616..1648
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1683..1715
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1716..1748
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1749..1781
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1469..1497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1839..1884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2081..2128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2140..2231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1859..1876
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2081..2101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2140..2182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2190..2224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 131
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 134
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 151
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 152
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 154
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 168
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 169
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 189
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 190
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 192
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 206
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT BINDING 207
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-1"
FT DISULFID 22..31
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 60..69
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 80..97
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 99..108
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 115..128
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2"
FT DISULFID 122..137
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2"
FT DISULFID 139..148
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2,
FT ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 155..166
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2"
FT DISULFID 160..175
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2"
FT DISULFID 177..186
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2,
FT ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 193..204
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2"
FT DISULFID 198..213
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2"
FT DISULFID 215..224
FT /evidence="ECO:0000256|PIRSR:PIRSR002279-2,
FT ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 253..262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 269..279
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 290..299
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 328..337
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 344..354
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 365..374
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 403..412
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 419..429
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 440..449
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 478..487
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 516..525
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 537..554
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 556..565
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 594..603
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 632..641
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 670..679
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 708..717
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 746..755
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 784..793
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 832..841
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 870..879
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 908..917
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 954..963
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 975..992
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 994..1003
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1035..1044
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1073..1082
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1096..1113
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1115..1124
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2231 AA; 239479 MW; BC21D464622F41B5 CRC64;
MPNACQNGGT CHNTHGGYNC VCVNGWTGED CSENIDDCAS AACFQGATCH DRVASFYCEC
PHGRTGLLCH LNDACISNPC NEGSNCDTNP VNGKAICTCP SGYTGPACSQ DVDECALGAN
PCEHAGKCLN TLGSFECQCL QGYTGPRCEI DVNECISNPC QNDATCLDQI GEFQCICMPG
YEGVYCEVNT DECASSPCLH NGHCVDKINE FLCQCPKGFS GHLCQYDVDE CASTPCKNGA
KCLDGPNTYT CVCTEGYTGT HCEVDIDECD PDPCHYGSCK DGVATFTCLC QPGYTGHHCE
TNINECHSQP CRHGGTCQDR DNSYLCLCLK GTTGPNCEIN LDDCASNPCD SGTCLDKIDG
YECACEPGYT GSMCNVNIDE CAGSPCHNGG TCEDGIAGFT CRCPEGYHDP TCLSEVNECN
SNPCIHGACR DGLNGYKCDC APGWSGTNCD INNNECESDP CVNGGTCKDM TSGYVCTCRE
GFSGPNCQTN INECASNPCL NQGTCIDDVA GYKCNCPLPY TGATCEVVLA PCATSPCKNS
GVCKESEDYE SFSCVCPTGW QGQTCEIDIN ECVKSPCRHG ASCQNTNGSY RCLCQAGYTG
RNCESDIDDC RPNPCHNGGS CTDGINMAFC DCLPGFQGAF CEEDINECAS NPCRNGANCT
DCVDSYTCTC PAGFNGIHCE NNTPDCTESS CFNGGTCVDG INSFTCLCPP GFTGSYCQYD
VNECDSRPCL HGGTCQDSYG TYKCTCPQGY TGLNCQNLVR WCDSAPCKNG GKCWQTNTQY
HCECRSGWTG LNCDVLSVSC EVAAQKRGID VTLLCQHGGL CVDEEDKHYC HCQAGYTGSY
CEDEVDECSP NPCQNGATCT DYLGGFSCKC VAGYHGSNCS EEINECLSQP CQNGGTCIDL
TNTYKCSCPR GTQGVHCEIN IDDCHPHLDP TSRSPKCFNN GTCVDQVGGY SCTCPPGFVG
ERCEGDVNEC LSNPCDPRGT QDCVQRVNDF HCECRAGHTG RRCESVINGC RGKPCKNGGV
CAVASNTARG FICRCPAGFE GATCENDART CGSLRCLNGG TCISGPRSPT CLCLGSFTGP
ECQFPASSPC VGSNPCYNQG TCEPTSESPF YRCLCPAKFN GLLCHILDYS FTGGAGRDIP
PPQIEEACEL PECQEDAGNK VCSLQCNNHA CGWDGGDCSL NFNDPWKNCS QSLQCWKYFS
DGHCDSQCNS AGCLFDGFDC QRTEGQCNPL YDQYCKDHFS DGHCDQGCNS AECEWDGLDC
AEHVPERLAA GTLVLVVLLP PEQLRNNSFH FLRELSHVLH TNVVFKRDAQ GQQMIFPYYG
REEELRKHPI KRSAAGWTTS SLLPSASGGR QRRELDPMDI RGSIVYLEID NRQCVQSSSQ
CFQSATDVAA FLGALASLGT LNIPYKIEAV KSETVEPPLP PQLHLMYVAA AAFVLLFFVG
CGVLLSRKRR RQHGQLWFPE GFKVSEASKK KRREPLGEDS VGLKPLKNAS DGALMDDNQN
EWGDEDLETK KFRFEEPVVV PDLDDQTDHR QWTQQHLDAA DLRMSAMAPT PPQGEVDADC
MDVNVRGPDG FTPLMIASCS GGGLETGNGE EEEDAPAVIS DFIYQGASLH NQTDRTGETA
LHLAARYSRS DAAKRLLEAS ADANIQDNMG RTPLHAAVSA DAQGVFQILL RNRATDLDAR
MHDGTTPLIL AARLAVEGML EDLINSHADV NAVDDLGKSA LHWAAAVNNV DAAVVLLKNG
ANKDMQNNKE ETPLFLAARE GSYETAKVLL DHFANRDITD HMDRLPRDIA QERMHHDIVR
LLDEYNLVRS PQLHGTALGG TPTLSPTLCS PNGYLGNLKS ATQGKKARKP STKGLACGSK
EAKDLKARRK KSQDGKGCLL DSSSMLSPVD SLESPHGYLS DVASPPLLPS PFQQSPSMPL
SHLPGMPDTH LGISHLNVAA KPEMAALAGS SRLAFEPPPP RLSHLPVASS ASTVLSTNGT
GAMNFTVGAP TSLNGQCEWL PRLQNGMVPS QYNPLRPGVA SGTLSTQAAG LQHGMMGPLH
SSLSTNTLSP MIYQGLPNTR LATQPHLVQT QQVQPQNLQI QPQNLQPPSQ PHLSVSSAAS
GHLGRSFLGG EHSQADVQPL GPGSLPVQHT ILPQESQALP TSLPSSMVPP MTTTQFLTPP
SQHSYSSSPV DNTPSHQLQV PEHPFLTPSP ESPDQWSSSS PHSNISDWSE GISSPPTSMP
SQITHIPEAF K
//
