ID   A0A3Q0D9I0_MESAU        Unreviewed;       663 AA.
AC   A0A3Q0D9I0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Leucine-rich repeat flightless-interacting protein 1 isoform X22 {ECO:0000313|RefSeq:XP_021089812.1};
GN   Name=Lrrfip1 {ECO:0000313|RefSeq:XP_021089812.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021089812.1};
RN   [1] {ECO:0000313|RefSeq:XP_021089812.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the LRRFIP family.
CC       {ECO:0000256|ARBA:ARBA00008275}.
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DR   RefSeq; XP_021089812.1; XM_021234153.1.
DR   AlphaFoldDB; A0A3Q0D9I0; -.
DR   STRING; 10036.ENSMAUP00000006054; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   Gene3D; 1.20.5.4090; -; 1.
DR   InterPro; IPR019139; LRRFIP1/2.
DR   PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR19212:SF5; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF09738; LRRFIP; 3.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT   REGION          81..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          284..461
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          514..541
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          565..641
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        81..99
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   663 AA;  75018 MW;  B6657918F2B2FA43 CRC64;
     MTSPAGAKNQ EIDCLSPEAQ RLAEARLAAK RAARAEAREI RMKELERQQK EIYQVQKKYY
     GLDTKWGDIE QWMEDSERYS RRFRRNTSAS DEDERLSVGS RGSLRAQPEP EYGSSYTWTN
     GYDGDYCGSQ SLSRRSGRNS SYSGGDGRVS ALSSSREEKL GLSCSDLGLP SSGLACKPLS
     AQNGTRTSSM LDESSLYGAR RGSACGSRAP SEYSSHLNSS SRASSRASSA RASPVVEERP
     DKDFTEKGSR NMPSLSAATL ASLGGTSSRR GSGDTSISMD TEASIREIKE LNELKDQIQD
     VEGRYMQGLK EMKDSLAEVE EKYKKAMVSN AQLDNEKTNF MYQVDTLKDM LLELEEQLAE
     SQRQYEEKNK EFEREKHAHS ILQFQFAEVK EALRQREEML EEIRQLQQKQ AGFVREISDL
     QETIEWKDKK IGALERQKEF FDSIRSERDD LREETVKLKE ELKKHGIILN SEIATNGETS
     DTLNGVGYQG PTKMTKEELN ALKSAGEGTL DVRLKKLIDE RECLLEQIKK LKGQLEGRQK
     NGKDLLRSED GILENGTDVH VLDLQRDANR QISDLKFKLA KSEQEITALE QNVIRLESQV
     TRYRSAAENA EKIEDELKAE KRKLQRELRS ALDKTEELEV SNGHLVKRLE KMKANRSALL
     SQQ
//