ID A0A3Q0DAK4_MESAU Unreviewed; 792 AA.
AC A0A3Q0DAK4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Metastasis suppressor protein 1 isoform X7 {ECO:0000313|RefSeq:XP_021090162.1};
GN Name=Mtss1 {ECO:0000313|RefSeq:XP_021090162.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021090162.1};
RN [1] {ECO:0000313|RefSeq:XP_021090162.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_021090162.1; XM_021234503.1.
DR AlphaFoldDB; A0A3Q0DAK4; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF02205; WH2; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 48..277
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 764..781
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 282..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..671
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..738
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 86052 MW; 17C01E3A2F2B7315 CRC64;
MNSPWSSRWL SATVSRRCSP DITEEASPPK TAEAAAAADF PPCWEHQGSY PVWEDFINKA
GKLQSQLRTT VVAAAAFLDA FQKVADMATN TRGGTREIGS ALTRMCMRHR SIEAKLRQFS
SALIDCLINP LQEQMEEWKK VANQLDKDHA KEYKKARQEI KKKSSDTLKL QKKAKKVDAQ
GRGDIQPQLD SALQDVNDKY LLLEETEKQA VRKALIEERG RFCAFISMLR PVIEEEISML
GEITHLQTIS EDLKSLTMDP HKLPSSSEQV ILDLKGSDYS WSYQTPPSSP STTMSRKSSV
CSSLNSVNSS DSRSSGSHSH SPSSHYRYRS SNLAQQAPVR LSSVSSHDSG FISQDAFQSK
SPSPMPPEAA NQFSNGFSHG SLSSESHAGP VPHCLPASRL LPRVTSVHLP DNAHYYTIGP
GMLPSSQIPS WKDWAKPGPY DQPLVNTLQR RKEKREADSN GGGPATTGGP PAAAEEMQRP
RSMTVSAATR PGEEMEACEE LALALSRGLQ LDMQRSSRDS LQCSSGYSTQ TTTPCCSEDT
IPSQGTRRPA CRPALRATPV SDYDYFSVSG DQEAEQQEFD KSSTIPRNSD IGQSYRRMFQ
AKRPASTAGL PTTLGPAMVT PGVATIRRTP STKPSVRRGT IGAGPIPIKT PVIPVKTPTV
PDLPGVLPSP PDGPEERGEH SPESPSVGEG PQGVANIPSS LWSGQASVNP PLPGPKPCIP
EEHRQAIPES EAEDQERDPP SATVSPGPTP ESDPADLSPR ESPQGEDMLN AIRRGVKLKK
TTTNDRSAPR LS
//
