ID A0A3Q0DFY0_MESAU Unreviewed; 1441 AA.
AC A0A3Q0DFY0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Protein Shroom4 isoform X1 {ECO:0000313|RefSeq:XP_021091626.1};
GN Name=Shroom4 {ECO:0000313|RefSeq:XP_021091626.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021091626.1};
RN [1] {ECO:0000313|RefSeq:XP_021091626.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the shroom family.
CC {ECO:0000256|ARBA:ARBA00006469}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_021091626.1; XM_021235967.1.
DR STRING; 10036.ENSMAUP00000005501; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.250.3120; -; 1.
DR InterPro; IPR014799; ASD2_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR027685; Shroom_fam.
DR PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR PANTHER; PTHR15012:SF35; PROTEIN SHROOM4; 1.
DR Pfam; PF08687; ASD2; 1.
DR PROSITE; PS51307; ASD2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 1..41
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1156..1435
FT /note="ASD2"
FT /evidence="ECO:0000259|PROSITE:PS51307"
FT REGION 151..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 735..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1039..1058
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1352..1379
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 178..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..665
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1065..1083
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1086..1101
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1441 AA; 159698 MW; 967496E3BF10AB18 CRC64;
MRTGDELVNI NGTPLYGSRQ EALILIKGSF RILKLIVRRR NIPVSRPHSW HVAKLLEGCP
EAATTMHFPS EAFSLSWHSG CNTSDVCVQW CPLSRHCSTE KSSSIGSMES LEQPGQATYE
GHLLPIDQNM YPSQRDSAYS SFSASSNASD CALSLRPEEP PSTDCVMSGP GQTKAIDGRP
NVSETSGSSH STSGDHETSA SHESSCPEEG QHSGPAKMVQ GPPEPPVRRD SLQASRSQLL
NGEQRRASEP VDSLQQKEKQ GLDTALSTRN PNQFCCVSGQ DQVTGEGHQN CEPIQPSESS
QEDSEHLLIE GSSKALDSPK THDKGSSREF SLVKEASADL VNTLTFGAIP RLRGTTEHRH
SAPEQLLASH LQQVHLDSRG SKGMELPTGQ DGHQWTVSPL HNISKGKKSP GFLTGDTQDQ
PSNERKTKLI DDKLMGLVHR SQSGSPLGEV DGHLPERTYL DPNRASRTGS DLASQQPSAT
CSSIQQARDF FSTSKVAGHA ETTEEGNSEA KECGQLGGRR SGGPRGRSIQ NRRKSERFAT
NLRNEIQRRK AQLQKSKGPL SQFCDTKEPV QETQEPPESP PLSASNSSLL SSHKNVPSPG
DKLFNKNMML RARSSECLSQ ASESSKARVD LEGRISPGQR SGHSSLGLNT WWKASDSSSL
DTDKANAPQG VCGGHWRWSP EYNPQPQVPL STEGSSSPDD NKESKTSTAQ AGEEAILLPF
ADRRKFFEES SKSLSTSHLP GLTTHSNKTF PQRPKPIDQN FQSVSYRELR CHPLDQSYHS
TDQPYHAADQ PYHAMSPLQS ETPTYPECFA TKGLENSLCC KTLHCGDFDY HRTCSYSCSV
QGTVMHDPCI YCSGEICPAL LKRNLLPNCH NCRCHHHQCI RCTACYHNPQ HGVLEDSSLA
SGNAWKPRKA SLQEFPGDKW KPIAGNRKTS HSGREMVHSK ASFSWSTPFH PCLENPALDL
SNYRAVSSLD LLGDFKLALN KAEESSVYED GSSVASMPRP LRSRAFSESH ISLEPQNTRA
WGKPQREPFA KGNETQPELL GARKKAFPPP RPPPPNWEKY RLFRAAQQQQ QQQQQQQQQQ
QQRCDEEEGI EEEEKEQEQE EGVKEEDLPP QYFSSETPGS RAPNLDEGLE QPQTLKLGHL
ETSRQATQSL PEQEAFALHP SDFVPPLRGH TGAQPEKAQP PCYHGTHGLW RTTEQEATVT
PKQEFQHFSP PPGAPGIPTS YSAYYNISVA KAELLNKLKE QPEMAEAGLG EEGVDYELAQ
KKIQLIESIG RKLSVLREAQ RGLLDDINAN SALGEEVEAN LKAVCKSNEL EKYHLFIGDL
DKVVNLLLSL SGRLARVENA LNSIDSETNQ EKLVLMEKKQ QLTSQLADAK ELKEHVDRRE
KLVFSMVSRY LPQDQLQDYQ HFVKMKSALI IEQRELEEKI KLGEEQLRCL KESLHLGPNN
F
//
