ID A0A3Q0DH47_MESAU Unreviewed; 529 AA.
AC A0A3Q0DH47;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Prickle-like protein 3 isoform X2 {ECO:0000313|RefSeq:XP_021091644.1};
GN Name=Prickle3 {ECO:0000313|RefSeq:XP_021091644.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021091644.1};
RN [1] {ECO:0000313|RefSeq:XP_021091644.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the prickle / espinas / testin family.
CC {ECO:0000256|ARBA:ARBA00008268}.
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DR RefSeq; XP_021091644.1; XM_021235985.1.
DR AlphaFoldDB; A0A3Q0DH47; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09415; LIM1_Prickle; 1.
DR CDD; cd09418; LIM2_Prickle; 1.
DR CDD; cd09420; LIM3_Prickle; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR033725; LIM1_prickle.
DR InterPro; IPR033726; LIM2_prickle.
DR InterPro; IPR033727; LIM3_prickle.
DR InterPro; IPR010442; PET_domain.
DR InterPro; IPR047120; Pk/Esn/Tes.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24211; LIM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24211:SF19; PRICKLE PLANAR CELL POLARITY PROTEIN 3; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF06297; PET; 1.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS51303; PET; 1.
PE 3: Inferred from homology;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 1..92
FT /note="PET"
FT /evidence="ECO:0000259|PROSITE:PS51303"
FT DOMAIN 94..159
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 160..219
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 326..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..445
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 58452 MW; 504D4AEE8E33144D CRC64;
MFTRGSRRRR SGRAVYQFFS CLPEDKVPYV NSPGEKYRIK QLLYQLPPHD SEAQYCTALQ
EEEKKELRAF SQQRKRENLG RGTVRIFPVT ITGAICEECG KQIGGGDIAV FASRAGLGAC
WHPQCFLCTT CQELLVDLIY FYHAGKVYCG RHHAECLRPR CQACDEIIFS PECTEAEGRH
WHMGHFCCFE CEASLGGQRY VMRQSRPHCC ACYEARHAEY CDGCGEHIGL DQGQMAYEGQ
HWHASDRCFC CSRCGRALLG RPFLPRRGLI FCSRACSLGA ETTAPGPGRR SWSAGTVTAP
LTASTASFPA AEGTSETASK GICTKAEPAA GSEEPSRFLR GAPHRHSMPE LGLRSAPEPP
TETPGHPALH PDDNAFGRQS TPRVSFRDPL VSEGGPRRTL SAPPAQRRRP RSPPPRAPSC
RHGRRRRRRR RGSHHHHHRP GRHGHYHCNA GSGSDSGSCS SSPSSPSSES SEDDGFFLGE
RIPLPPHLCR SRTSQDTATE TLSSPAPPLV QVSHPGMPRQ SRDKNCIVA
//
