ID   A0A3Q0EWB8_VIGRR        Unreviewed;       333 AA.
AC   A0A3Q0EWB8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Probable magnesium transporter {ECO:0000256|RuleBase:RU363078};
GN   Name=LOC106761647 {ECO:0000313|RefSeq:XP_022636038.1};
OS   Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX   NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_022636038.1};
RN   [1] {ECO:0000313|RefSeq:XP_022636038.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_022636038.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Acts as a Mg(2+) transporter. Can also transport other
CC       divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but
CC       to a much less extent than Mg(2+). {ECO:0000256|ARBA:ARBA00025284,
CC       ECO:0000256|RuleBase:RU363078}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738,
CC       ECO:0000256|RuleBase:RU363078}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363078};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363078}. Early
CC       endosome {ECO:0000256|RuleBase:RU363078}. Endosome
CC       {ECO:0000256|ARBA:ARBA00004177}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the NIPA (TC 2.A.7) family.
CC       {ECO:0000256|ARBA:ARBA00007001, ECO:0000256|RuleBase:RU363078}.
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DR   RefSeq; XP_022636038.1; XM_022780317.1.
DR   AlphaFoldDB; A0A3Q0EWB8; -.
DR   Proteomes; UP000087766; Chromosome 5.
DR   GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR008521; Mg_trans_NIPA.
DR   PANTHER; PTHR12570:SF11; MAGNESIUM TRANSPORTER NIPA6-RELATED; 1.
DR   PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR   Pfam; PF05653; Mg_trans_NIPA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU363078};
KW   Endosome {ECO:0000256|RuleBase:RU363078};
KW   Ion transport {ECO:0000256|RuleBase:RU363078};
KW   Magnesium {ECO:0000256|RuleBase:RU363078};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363078};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087766};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363078};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363078}; Transport {ECO:0000256|RuleBase:RU363078}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        47..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        78..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        104..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        143..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        172..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
FT   TRANSMEM        272..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363078"
SQ   SEQUENCE   333 AA;  36473 MW;  F8044384DBBBEBB3 CRC64;
     MGIAENSKGL VLAVASGVFI GASFILKKKG LKQAATNGTR VGGYSYLLQP FWWAGMVTMF
     IGEVANFVAY IYAPALLVTP LGALSIIVSA VLAHFLLKEK LQQMGILGCV FCIVGSVLIV
     IHAPQEHALN SVQEIWDLAT QPLFLVYVTV TVSIILALIL HFEPRYGQKN MLVYLGICSL
     MGSLTVMSTK AIGIAIKLTL EGISQLTYPQ TWFFLTVAVI CIITQLNYLN KALDTFNTAI
     VSPVHYVMFT TLTIIASVIM FKDWSDQSAS SIASEICGFI IVLSGTILLH ATREKEQPNM
     RGSLTWYIGE DLVKGIEDER LNLIIHGSDY IEQ
//