ID A0A3Q0F2J4_VIGRR Unreviewed; 721 AA.
AC A0A3Q0F2J4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=CSC1-like protein RXW8 isoform X2 {ECO:0000313|RefSeq:XP_022638235.1};
GN Name=LOC106764810 {ECO:0000313|RefSeq:XP_022638235.1};
OS Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_022638235.1};
RN [1] {ECO:0000313|RefSeq:XP_022638235.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_022638235.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR RefSeq; XP_022638235.1; XM_022782514.1.
DR AlphaFoldDB; A0A3Q0F2J4; -.
DR Proteomes; UP000087766; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF117; CSC1-LIKE PROTEIN RXW8; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087766};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..164
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 185..339
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 350..617
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 686..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..721
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 721 AA; 81824 MW; 86D893FB1A48F477 CRC64;
MDINALLTSA GINIALCVVL FSFYSVLRKQ PSNVNVYFGR RLASQHSRRV DVCLERFVPS
PSWILKSWET TEEEILAIGG LDAVVFVRML VFSIRVFSIA AVICLALVLP INYHGRDRTH
KYIPFESLEV FTIENVKEGS TWLWAHCLAL YVITFSACTL LYIEYKSITN LRLLHIVGSP
PNPSHFTILV RSVPWSSEES YCETVKKFFS HYHASAYLSH QMIYKSGKVQ KLKDDAEHVC
KVLKNASLEK TCKPSFRHCC SGASTNSFKK ISNEMDSVNG GTDNTDMNLE TTKKECAAAF
VFFKSRYAAL MAAKVLQTPN PMLWVTDVAP EPHDIYWSNI CVPYRQLWIR KIATLVASIA
FMLVFLIPVT FVQGLTQLDK LQKMFPFLRG IFKEKIVNQV VTGYLPSVIL VLFFCAVPPM
MMLFSSVEGS ISRSERKKSA CCKVLYFTIW NVFFVNVFTG SVITQLSVFT SVTDLPAQLA
KAVPSQATFF TTYVLSSGWA SLACEVIQIF PLLCNIFQRF ILRLKEDALD SSLSFPYHTE
VPRVLLFGFL GFTCSILAPL MLPFLLFYFF LAYLVYRNQI INVYITKYDS GGQFWPIAHN
TTVFSLIFSQ LIALGVFGLK RSSVASGFTI PLLIGTLLFH QYCRQRFLPI FKSNSAQIVI
DMDMRDEHSG RMEEIYEHLP VAYNQPSLTE EDASSQPQCD KRHEDMDRGQ SSSEDMEKEG
K
//
