ID A0A3Q0FCX2_VIGRR Unreviewed; 225 AA.
AC A0A3Q0FCX2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=2-oxoglutarate dehydrogenase, mitochondrial-like {ECO:0000313|RefSeq:XP_022640212.1};
GN Name=LOC111242140 {ECO:0000313|RefSeq:XP_022640212.1};
OS Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_022640212.1};
RN [1] {ECO:0000313|RefSeq:XP_022640212.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_022640212.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- SIMILARITY: Belongs to the alpha-ketoglutarate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00006936}.
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DR RefSeq; XP_022640212.1; XM_022784491.1.
DR AlphaFoldDB; A0A3Q0FCX2; -.
DR STRING; 3916.A0A3Q0FCX2; -.
DR KEGG; vra:111242140; -.
DR OrthoDB; 3597773at2759; -.
DR Proteomes; UP000087766; Chromosome 7.
DR GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:UniProtKB-EC.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 3.40.50.12470; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR23152:SF4; 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1; 1.
DR PANTHER; PTHR23152; 2-OXOGLUTARATE DEHYDROGENASE; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000087766};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 69..155
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 225 AA; 25970 MW; B49D1FDCB5F9BB54 CRC64;
MKEMFDRASD LGVESIVMGM AHRGRLNVLG NVVRKPLRQI FCEFSGGQPA DEAGLYTGTG
DVKYHLGTSY EWRQTFHSDV VVDLVCYRRF GHNEIDEPSF TQPKMYKVIR NHPSALEIYQ
KKLLEFGELT REDIDKIHKK VTSILNDEFL ASKDYVPKIR DWLSAYWSGF KSPEQISRIW
NTGVKPEILK NVGKAITLLP ENFNPHKAVK RIYEQRSQMV ETGED
//
