ID A0A3Q0FLH6_ALLSI Unreviewed; 932 AA.
AC A0A3Q0FLH6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=LOW QUALITY PROTEIN: zinc fingers and homeoboxes protein 3 {ECO:0000313|RefSeq:XP_025047025.1};
GN Name=ZHX3 {ECO:0000313|RefSeq:XP_025047025.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025047025.1};
RN [1] {ECO:0000313|RefSeq:XP_025047025.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the ZHX family. {ECO:0000256|ARBA:ARBA00007440}.
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DR RefSeq; XP_006016716.1; XM_006016654.2.
DR RefSeq; XP_025047025.1; XM_025191240.1.
DR STRING; 38654.A0A3Q0FLH6; -.
DR KEGG; asn:102370118; -.
DR InParanoid; A0A3Q0FLH6; -.
DR OrthoDB; 5350395at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 4.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 5.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR024578; Homez_homeobox_dom.
DR InterPro; IPR041057; ZHX_Znf_C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR15467:SF6; ZINC FINGERS AND HOMEOBOXES PROTEIN 3; 1.
DR PANTHER; PTHR15467; ZINC-FINGERS AND HOMEOBOXES RELATED; 1.
DR Pfam; PF00046; Homeodomain; 4.
DR Pfam; PF11569; Homez; 1.
DR Pfam; PF18387; zf_C2H2_ZHX; 1.
DR SMART; SM00389; HOX; 5.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 5.
DR PROSITE; PS50071; HOMEOBOX_2; 4.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 299..342
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 481..531
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 597..645
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 738..798
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 301..343
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 483..532
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 599..646
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 740..799
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 25..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 650..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..932
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 932 AA; 103478 MW; 40638E951A80DB11 CRC64;
MASKRKSTTP CMIPVKKLVL QETESDVVED DRGGIQQDTR PEAPAASDTV VNHNNNGTLS
NGHRSLAEGD TYVCKYCEFG SQDVNHFFGH MDSEHLDFSK DPLLVCTECS FLAKSHERLL
QHNAECHAGE TGFVWNVVKQ DNRTTVEQSI CDATSNQDLP GEIPGEGVDS QAEIIITKTP
IMKIMKGKAE AKKIHTLKEN ITNQSANEPE MKNGDHLFTN GSVPVSQSVP SSAKPSPIVN
GSIIGSVPVL QTGVAHLVPL QQQPLLHQQL PTSKSLPKVM IPLSSIPTYN AAMDSNSFLK
NSFHKFPYPT KAELCYLTVV TKYPEEQLKI WFTAQRLKQG ISWSPEEIED ARKKMFNTVI
QSVPQPTITV LNTPLVANTS SVPHLIQATL PGHVVGQPEG TGGLLVTQPI MTNELKGTNS
SLTLTVTSIP KLQPVTQHNT VCSNTASTVK VVNTAQSLLT ACPTISSQAF LDPNVYKNKK
SHEQLSALKG SFGRNPFPGH AEVERLTKIT GLSTREVRKW FSDRRYHNRN VKGGRGMFVG
DNTIDSLTEM TFPVSTKGTE LTSMTAATPV THHHTRRQSW HQTPDFTPTK YKERAPEQLK
ALEGSFAQNP FPSEEEVDRL RSETKMTRRE IDSWFSERRK KKLAEENKKV DEMVQQEEEX
XXXXXXXXXX XSDELRASSE NGSVDMPGSS QTAAERKVSP IKINLKKLKV TESNGKNELQ
GLSANKKGDS PSSRPPTPHK TKLNLKKTAQ QRHLLKQMFV QTQRPTNQEY DAIVAQTGLP
RAEVIRWFGD SRYGYKNGQL KWYENYRRGI FPPGLAEISP DSKELLEDYY KKHKMLCEDD
LQTLCERTQL NSQRVRVWFA VKVDEETRAV SDTGSEDRCS SSGDAAGNPK GTSDACSEMS
ENSESWEPGG QEGSSDPSDT FSQQPTVPLE TD
//
