ID A0A3Q0FUU0_ALLSI Unreviewed; 357 AA.
AC A0A3Q0FUU0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=H-2 class I histocompatibility antigen, Q9 alpha chain-like isoform X1 {ECO:0000313|RefSeq:XP_025049920.1};
GN Name=LOC102379493 {ECO:0000313|RefSeq:XP_025049920.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025049920.1};
RN [1] {ECO:0000313|RefSeq:XP_025049920.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in the presentation of foreign antigens to the
CC immune system. {ECO:0000256|ARBA:ARBA00002297}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|ARBA:ARBA00006909, ECO:0000256|RuleBase:RU004439}.
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DR RefSeq; XP_025049920.1; XM_025194135.1.
DR AlphaFoldDB; A0A3Q0FUU0; -.
DR STRING; 38654.A0A3Q0FUU0; -.
DR KEGG; asn:102379493; -.
DR InParanoid; A0A3Q0FUU0; -.
DR OrthoDB; 3840485at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675:SF242; CLASS IB MHC ANTIGEN QA-2-RELATED; 1.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022451};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW MHC I {ECO:0000256|ARBA:ARBA00022451};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 149..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 169..343
FT /note="MHC class I-like antigen recognition-like"
FT /evidence="ECO:0000259|Pfam:PF00129"
FT REGION 64..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 39430 MW; BE717EEC95CACE97 CRC64;
MVPTWPVAEE ETEVATTWEE LEAAGDAEQA AHGSDPFPGG WCLPRGKKMT TFSGSFLLPA
EAQPVSLSPG SNTCKGPPNQ DYNTNQEAHE SQALGPAHTA PSPSAPQSDP AAPCSPLHPS
LCGSTCNSCA QRPEAPHEAS AKVAPGSRLL LLLLLLVGIA AVPGIGAGSQ SYWYFYMGVS
DPGPDMLDFT AVGYMGDQQI LHYNSETQRQ EPRGNWVQGA VGLDSWNRET RTLQGRQEVF
KWNLLALQHH YKQTSGSHTL QFMYGCQLGE DGCTRRYMQF GYDGGDFISY DLGMRTSVAE
TTQAQVTQRK WNEDKYRLQY LRAYLEGTCI EWLRQYLQHR EAILQSSESR CHRPGQH
//
