ID   A0A3Q0FWI3_ALLSI        Unreviewed;       894 AA.
AC   A0A3Q0FWI3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=NACHT, LRR and PYD domains-containing protein 3-like isoform X1 {ECO:0000313|RefSeq:XP_025050519.1, ECO:0000313|RefSeq:XP_025050520.1};
GN   Name=LOC102378507 {ECO:0000313|RefSeq:XP_025050519.1,
GN   ECO:0000313|RefSeq:XP_025050520.1, ECO:0000313|RefSeq:XP_025050521.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025050520.1};
RN   [1] {ECO:0000313|RefSeq:XP_025050519.1, ECO:0000313|RefSeq:XP_025050520.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NLRP family.
CC       {ECO:0000256|ARBA:ARBA00008665}.
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DR   RefSeq; XP_014382554.1; XM_014527068.1.
DR   RefSeq; XP_025050519.1; XM_025194734.1.
DR   RefSeq; XP_025050520.1; XM_025194735.1.
DR   RefSeq; XP_025050521.1; XM_025194736.1.
DR   STRING; 38654.A0A3Q0FWI3; -.
DR   KEGG; asn:102378507; -.
DR   OrthoDB; 55870at2759; -.
DR   Proteomes; UP000189705; Unplaced.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR   PANTHER; PTHR45690:SF15; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   SMART; SM00368; LRR_RI; 5.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT   DOMAIN          247..380
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   894 AA;  101143 MW;  0AB9C2642AF16A6B CRC64;
     MASDQRRMVS EGDVTAFSVH LHNYTTSELR RLSEYFLPDL VYIIENDVRA VLQELSSRNV
     LMAWQAQSYA AWEKDHDAAS AAEKLVADIL TQGQDAGLGL WKCLYALQSR WSHPNLHGMV
     DEILENGHNL LNEILLNEYG YVLDPELTAC QEAHKAQLRE MTGDLKENAA PGLSQGPQSF
     PISSRYVEIK VISDRDFKKQ IHHEHEALAA AGELNEYRLQ RRTRTALERI TPDRLFRWCP
     RSRRVPLSVM VSGVAGVGKT TLVQKFVFDW ATGKHYQKFA FVFFFKFRDL MEEKVSLESL
     LCKTYPRLRA QLGKVLGDPE KLLFIFDGLD ESKGGLKLTG SGSDELCRTL GDIKPAWVLV
     ASLLRQTLLK GCSVLLTSRP QNLASLGTGV FQRVASIVGF LAKERERYFS MFFGDEKVSQ
     EAFRYVRDSQ VLYTLCYNPS YCWITCTALK PCFATRDGKP PPAPKTVTQL FMCYITHILA
     NHSLEQPKLQ VMRDALTQVG WLADYGITNR ILVFDDNYMQ AFNVKFYPFL TGFLAENPKS
     QAPSLVTYSF LHLTVQEFLA ALVYYLDYNK DNLVDMLARA RACKEGTYEI FLRFLTGLCH
     PATRAPLERF LGKLSADAAH HVITWLSEFN CQAVQNSAGP VGQRKLMNVF TLLFESRNRQ
     LVCDVLGLNV CLDFTKFHLM LVDCTVLGYI LSCCEEVERL TLNACFIQDA GLEQLGPELH
     KVRELSLVDN DLKDPSMKVI CGALKWPDCR MEALSLKDNA FTSDCCEDLA FALKENQSLL
     SLDLGKNKVL DSGLSYLCQA FEDPHCRMQK LLLQGTGLSN FSCQILSYAL ATNTSLQHLN
     LSSNMFTDEC AEEMRQLILT CPYLKEIRLG FCDFTPAMEE HLKKLAVEGV KISF
//