ID A0A3Q0FXC9_ALLSI Unreviewed; 501 AA.
AC A0A3Q0FXC9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Mesoderm induction early response protein 2 isoform X6 {ECO:0000313|RefSeq:XP_025052226.1};
GN Name=MIER2 {ECO:0000313|RefSeq:XP_025052226.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025052226.1};
RN [1] {ECO:0000313|RefSeq:XP_025052226.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025052226.1; XM_025196441.1.
DR AlphaFoldDB; A0A3Q0FXC9; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR10865:SF27; MESODERM INDUCTION EARLY RESPONSE PROTEIN 2; 1.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 128..225
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 230..282
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 28..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 55416 MW; 42DEC53CE4485AAD CRC64;
MNQHWWIHWS EMPFEELLAL YGYEASDPIS EQDSESNGIS PHLPDMTLDK EQIAKDLLSG
EEEEETQSSA DDLTPSVTSH DASDLFPNQP GSNNFLADED KEPCSSPCAS SMAEDSEEDS
IPSNECKKEI MVGPQYQAAV PILHLQRHSE KVYENEDQLL WDPNILPEKE VEEFLYRAVK
RQWDELASIS LPEGEMVKDN EQALYELVKC NFNAEEALRR LRFNVKVIRD ELCAWSEEEC
RNFEHGFRVH GKNFHLIQAN KVRTRSVGEC VEYYYMWKKS ERYDYFTQQT RFGRKKYVLH
PGATDYAEND LDGGEVENAG RARSSPPIPS ATSCLDSHFS QDPLAIESTE PLSVESAACS
LGSMSESGQG YECSTPSETN CSFDPAEEPA SSTRRPGTPS ETGIYPLPPA GPDPVDKAET
LQSSGETIAV DFTLPADMGE GLPLIAGRVD LGTAPEAVVA PAQVSLSVTD FSIIGIGDVN
SFLAAHQACP APVAQSEPLS Q
//
