ID A0A3Q0G1I3_ALLSI Unreviewed; 749 AA.
AC A0A3Q0G1I3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transducin-like enhancer protein 1 isoform X5 {ECO:0000313|RefSeq:XP_025052235.1};
GN Name=LOC102385168 {ECO:0000313|RefSeq:XP_025052235.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025052235.1};
RN [1] {ECO:0000313|RefSeq:XP_025052235.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the WD repeat Groucho/TLE family.
CC {ECO:0000256|ARBA:ARBA00005969}.
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DR RefSeq; XP_025052235.1; XM_025196450.1.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR005617; Groucho/TLE_N.
DR InterPro; IPR009146; Groucho_enhance.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10814; TRANSDUCIN-LIKE ENHANCER PROTEIN; 1.
DR PANTHER; PTHR10814:SF4; TRANSDUCIN-LIKE ENHANCER PROTEIN 2; 1.
DR Pfam; PF03920; TLE_N; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR01850; GROUCHOFAMLY.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 34..148
FT /note="Groucho/TLE N-terminal Q-rich"
FT /evidence="ECO:0000259|Pfam:PF03920"
FT REPEAT 509..542
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 553..594
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 595..636
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 145..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 42..69
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 196..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..261
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 749 AA; 80088 MW; E88FEFE38938CD69 CRC64;
MFSQNRPPAH LQAPPVATAA AVAASAVSST PQSLKLTYPE TLDRIKEEFQ FLQNQYHSLK
LECEKLATEK TEIQRHYVMY YEMSYGLNIE MHKQTEIAKR LNVICAQLIP FLSQEHQQQV
VQAVERAKQV TMAELNAAIG HQLQAQHLSH HAPPIPLTPH PSGMQSSTLA SIGSASGLLA
LSGALGAQAQ LVPKDDRGLL DTEHRERDPG PSALALPNGE RARTLSDYLS GSKKRKAEEK
GFVIDYGSDA DKSEDNLVVD EDPASPHSVH SYSSRENGAE KGPLGRKEAM PLSPTSMASS
RSTSPSRSKD PPTVEKAGTP GLKSSTPTSQ GDSAGPGSSS SSSVGQQFRP SAAKTSVDSL
ALGLRNPLAM QSSYPAAFSM AHPSVNGDMA SAGTYAGLQL MSPQLNGAAA AAGGYGRSPP
VGYDPHPHMR VPGLAAGMQA GTSGKPAYSF HVSADGQMQP VPFPPDALLG SGIPRHARQL
HTLTHGEVVC AVTISSSTRH VYTGGKGCVK NRDNYIRSCK LLPDGRSLIV GGEASTLSIW
DLAAPTPRIK AELTSSAPAC YALAISPDAK VCFSCCSDGN IVVWDLQNQT LVRQFQGHTD
GASCIDISND GTKLWTGGLD NTVRCWDLRE GRQLQQHDFS SQIFSLGYCP TGEWLAVGME
SSNVEILHVT KPDKYQLHLH ESCVLSLKFA ACGKWFVSTG KYNLLXXXXA SIFQSKESSS
VLSCDVSTDD QFIVTGSGDK KATVYEVIY
//
