ID A0A3Q0G1M3_ALLSI Unreviewed; 304 AA.
AC A0A3Q0G1M3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit D {ECO:0000256|ARBA:ARBA00018992};
DE AltName: Full=TATA box-binding protein-associated factor 1D {ECO:0000256|ARBA:ARBA00032499};
DE AltName: Full=Transcription initiation factor SL1/TIF-IB subunit D {ECO:0000256|ARBA:ARBA00030353};
GN Name=TAF1D {ECO:0000313|RefSeq:XP_025053676.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025053676.1};
RN [1] {ECO:0000313|RefSeq:XP_025053676.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the transcription factor SL1/TIF-IB complex,
CC which is involved in the assembly of the PIC (preinitiation complex)
CC during RNA polymerase I-dependent transcription. The rate of PIC
CC formation probably is primarily dependent on the rate of association of
CC SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
CC stabilization of nucleolar transcription factor 1/UBTF on rDNA.
CC Formation of SL1/TIF-IB excludes the association of TBP with TFIID
CC subunits. {ECO:0000256|ARBA:ARBA00025110}.
CC -!- SUBUNIT: Component of the transcription factor SL1/TIF-IB complex,
CC composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts
CC with UBTF. {ECO:0000256|ARBA:ARBA00025940}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_025053676.1; XM_025197891.1.
DR AlphaFoldDB; A0A3Q0G1M3; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005668; C:RNA polymerase transcription factor SL1 complex; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR027976; TAF1D.
DR PANTHER; PTHR14562; TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D; 1.
DR PANTHER; PTHR14562:SF3; TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D; 1.
DR Pfam; PF15333; TAF1D; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 34339 MW; 52E3A02297711D8B CRC64;
MTDADDSQSS VSDYFEDGRD LVCTEEEDQL PTHDAAVGRS AQLGSAREGA TSEDSSCALG
ARGTSATCFT QSAKASLESS DSESSPCSSG SLYQPECNTA SRRKVTTRRS ARNLSRSPAN
RQDSARQDSL TATPHSDLGC GKESKSSGLP KSSLDLKAIF AHHFRGKKLK SEANRRFKER
KQRTKKKYES TRRPRRRLLQ TMSREERKER LLGRGFQFPF VEKHYGRKHI PLKMVFEYEH
AALKGYFQYI EMLKYEDHLK KALKNLNASE DFESKCVAMR RHRYLDDEGP ISPIQDTKIT
AVSY
//
