ID A0A3Q0G2C5_ALLSI Unreviewed; 178 AA.
AC A0A3Q0G2C5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Vascular endothelial growth factor A isoform X6 {ECO:0000313|RefSeq:XP_025053617.1};
GN Name=VEGFA {ECO:0000313|RefSeq:XP_025053617.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025053617.1};
RN [1] {ECO:0000313|RefSeq:XP_025053617.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR RefSeq; XP_025053617.1; XM_025197832.1.
DR AlphaFoldDB; A0A3Q0G2C5; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd00135; PDGF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR PANTHER; PTHR12025; VASCULAR ENDOTHELIAL GROWTH FACTOR; 1.
DR PANTHER; PTHR12025:SF5; VASCULAR ENDOTHELIAL GROWTH FACTOR A; 1.
DR Pfam; PF00341; PDGF; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 41..137
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..178
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 178 AA; 20303 MW; 64D2D35FC24EC4EB CRC64;
MPLARLDTGM REPGGPGQKG GLKMLSQAAP TLGDGERKPN EVIKFLDVYE RSYCRTIETL
VDIFQEYPDE VEYIFKPSCV PLMRCAGCCG DEGLECVPGE VHNVTMEIMR IKPHQSQHIA
YMSFLQHSKC ECRPKKDVKA KQENFSSRKS KRGKGKGQKR KRKKGRYKPH SLCDKPRR
//
