ID A0A3Q0G772_ALLSI Unreviewed; 707 AA.
AC A0A3Q0G772;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=E3 ubiquitin-protein ligase RFWD3 isoform X2 {ECO:0000313|RefSeq:XP_025055539.1};
GN Name=RFWD3 {ECO:0000313|RefSeq:XP_025055539.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025055539.1};
RN [1] {ECO:0000313|RefSeq:XP_025055539.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025055539.1; XM_025199754.1.
DR AlphaFoldDB; A0A3Q0G772; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16450; mRING-C3HGC3_RFWD3; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037381; RFWD3.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16047:SF7; E3 UBIQUITIN-PROTEIN LIGASE RFWD3; 1.
DR PANTHER; PTHR16047; RFWD3 PROTEIN; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 266..310
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 35..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 77371 MW; 56006B0D26FDF35E CRC64;
MAAATGRLEL AAALREMAQE DMEVDLQPAV EEFPVQASGH SLLPLSANTP VPGEETEGIA
APPSPGETDD ESDPQLNGAS AVDRLQRLRG VLELFRLQAT QPVAQQEQHF PLLVSPTRRT
RHQQQRVGGS QRTGNARPRG RLDRYFSFSR TQRAATVAAP LLETLRLPVN NTGHSSDETV
ELSDSDSSSS SELGTTAAAQ EEAPAADGLR ASDQVQTEAP GALYSAEHES HNGEGATVQQ
KQTSPLKKPD TTVPTVPLDD EEGDICTICF EQWSNAGEHR LSALRCGHLF GYTCIDRWLK
GQAGKCPQCN KKAKRSDIVL LYARTLKALD TSEQERMKSS LEKEQVLRRQ AELESAQSRL
QLQVLTDECS KLRKQVQELK ALMAQHNTSA SQQPGSSRSY LPGTLPSSQS QHKYHFEKAF
LVSRSGSCRV MAYCDSLSCL VVSQPSPQST LIPGCGVKMM SAANLRSSQY IPIHSKQIRG
LAFSNRTHGL LLSASLDHTL RLTSLTTNTV VQTYDAGRPV WSCCWCLDDT NYIYAGLVNG
SILVYDLRDT RSHVQELVPQ KYRCPMVSLS YLPRMASASL PYGGVIAGTL EGACFWEQKD
NNSYRPHHLP VEPGGCIDIQ TEINTRHCLA TYRPNKNNPY LRCVVMELSC SPLTDASDII
ICSCHPVQTF SAGPTCKLLT KNAIFQSPEE NGRILVCAGD EASNSAM
//
