ID A0A3Q0G800_ALLSI Unreviewed; 677 AA.
AC A0A3Q0G800;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Cell surface glycoprotein MUC18 isoform X6 {ECO:0000313|RefSeq:XP_025055769.1};
GN Name=MCAM {ECO:0000313|RefSeq:XP_025055769.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025055769.1};
RN [1] {ECO:0000313|RefSeq:XP_025055769.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025055769.1; XM_025199984.1.
DR AlphaFoldDB; A0A3Q0G800; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11973:SF18; CELL SURFACE GLYCOPROTEIN MUC18; 1.
DR PANTHER; PTHR11973; CELL SURFACE GLYCOPROTEIN MUC18-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13927; Ig_3; 2.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 590..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 181..267
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 281..380
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 391..472
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 479..566
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 650..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 74540 MW; A8886A9E16F48561 CRC64;
MIWKHLEPQT SRFRHYHIKE KGKSKSEIIS GARSLECAIV LHRRPAEQTC QRGHGNPGNP
DTGYASKVEV STPSVVEVDL GHTAMLPCSF FILPDSNITY VYWSYIPRSS RTKVYSWVQG
KVFVDDSPYV GRVSMDDTFT LAITQTTLQD ARVFVCQVGA GSLGVGENRT ELRVYKAPEP
PEIHANEAGI SVGTRESQEI AECVVRNSFP GPNITWLKDG HRLHPEDDKV KIMDTRTQEA
SGLFTARSRL LAHVPRQDRH AYFQCQAHYL LAGGDRQAQS PKVQVHIFYP TENVSLAIDA
PRPQVKEGDH VALRCQGDGN PPPEYSFFRV QNNTATGEEE EQELSGKADK GVLSLGKVHK
ENTGHYRCKG LDLDTMETLT ADAELVVNYI EGLKVTKESP EPVLEGHNLT LTCEARGSRP
LAFHWHKDKK GKALGSGQQL QLSNIMREAA GNYICEVTMP GVQGLSRNKQ VLVVVYGKPQ
VSVEKPGVPV QENELVTLTC TALAQPEPSI TWSANGTVQN RTENYSVVSN LTVQVTSKLM
RSGINCTATN YLGVVTHHVH LERRMTPTTP TTTAPAGNAT AEQKPQESKG VIIVAVIVCI
LVLAVLGAVL YFLHKKGKIP CGRTGKQDIT KPDARKDEVV VEVKSDKLPE EAGLLQATNG
DQKPAGDQGE KYIDLRH
//
