ID A0A3Q0G9P2_ALLSI Unreviewed; 654 AA.
AC A0A3Q0G9P2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=BRCA1-associated RING domain protein 1 isoform X4 {ECO:0000313|RefSeq:XP_025055160.1};
GN Name=BARD1 {ECO:0000313|RefSeq:XP_025055160.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025055160.1};
RN [1] {ECO:0000313|RefSeq:XP_025055160.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025055160.1; XM_025199375.1.
DR AlphaFoldDB; A0A3Q0G9P2; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd17734; BRCT_Bard1_rpt1; 1.
DR CDD; cd16496; RING-HC_BARD1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039503; BARD1_Znf-RING.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24171; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED; 1.
DR PANTHER; PTHR24171:SF8; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF14835; zf-RING_6; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 41..78
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 442..474
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 475..507
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 508..540
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 72313 MW; C26CBCC80764FBB9 CRC64;
MQAALRARSG NRPLSPVMER PSRAWHHTRA ALEQLEAALR CSRCDHVLRE PVCLDQCEHV
FCLDCVGDCV GTECPVCHMP AWVQDVQINR QLNNMIQLCS KLRQLLGTDP ALPPDSAEDL
STSIRYNQDM GNKKQIKMWF SPRSRKIRCI LNKNQEVTNA DKISQDAPSV YDFSPSPSHE
KTSKQSKKPA RGLTKKLKKK RLADFNKVWG IEKEKQKDGS RPEEKEASDE FSGKKVSFCS
QPLVASTPEP KSTEKTLGQE SVKETNLNKN GSKSYLEMST QVKPVEDNDR NKVACPAEDI
IESGVTTGKP LPGRNKETLL KCGRQQSRSP ALSHSKRPRT SEKSTSRQSV TQQSPQNCCT
NMSLAAEDDS LVDISSVYKH TGGTVSKPKN SSAFKEINSP LVSKAQTTPS TPNNWNQMAV
TQSPSLSKKY PDQSTTTKRN HKGETLLHIA SIKGDLTAVE LLLKNGADPN VKDHAGWTPL
HEACNHGHKE VVELLLQHGA LVNTTGYHND SPLHDAAKNG HVSIVELLLL HGASHNALNI
FGLRPVDYAE TEKMKSVLML PGKNESSSFS QSVEQASPNH PKDGPVILLG SSLSSDKQKL
LSKLSAVLKA RRCMEFNSTV THVIVPDDSI RSTFKYMMAV LSGCWVLKFE YSRA
//
