ID A0A3Q0GET8_ALLSI Unreviewed; 4562 AA.
AC A0A3Q0GET8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Pericentrin isoform X6 {ECO:0000313|RefSeq:XP_025057982.1};
GN Name=PCNT {ECO:0000313|RefSeq:XP_025057982.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025057982.1};
RN [1] {ECO:0000313|RefSeq:XP_025057982.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR RefSeq; XP_025057982.1; XM_025202197.1.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR028745; AKAP9/Pericentrin.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR019528; PACT_domain.
DR PANTHER; PTHR44981:SF3; PERICENTRIN; 1.
DR PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR Pfam; PF10495; PACT_coil_coil; 1.
DR SMART; SM01188; ELK; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 322..347
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1211..1232
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1318..1339
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1386..1409
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1523..1544
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1552..1570
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1758..1778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4043..4069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4536..4562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 111..145
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 170..559
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 668..706
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 731..758
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 787..1121
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1262..1458
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1548..1688
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2006..2085
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2128..2206
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2433..2645
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2678..2846
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2904..2956
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3055..3124
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3243..3270
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3696..3925
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3958..3985
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4241..4316
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4562 AA; 532941 MW; E87AD68C1C66EDAE CRC64;
MEDEERQRKL EAGRAKLAHF RQRKTKSENT QSQKKAAKRK GSSIHTHDIP KEECTLVAQV
SDFLSDLGMS MESQTEDPDV SEASFEAKGD SDLPDPDVLD NHAVEELETA VQERNKIITR
LTSNLQQAQQ NQDDIQEETS LLTDQIHGLQ LQLLEADLLL KNKIPGKNEL AQAQQQMAVF
QNRLKEQSEH LQILHQKAHD LEVELESSQK NTKDKENLLA QMEENLKSTV QQLHKNIEEK
EETIKRLQDT VTSEKASLSM LKNTLSLRDT EITELKNEMA SAKMKEKEYV KELNMNHNND
ICRQLQELRA DLEESHRKEI LRLKEVCEEE INSKYKNELE QIKRELSAMN TDADIQKLNS
VIIDLNNQLH ESDSQRDNLS KKLKNQMLDF QRERSEIELR YKDLIDDLKL QLSNADEQIK
EAYECKQEKE HLNEEIYKLN SLIQELKEKL LLETETNTNL RQKHDEERTI YSMKLKKLEQ
EEKLLQEVSQ SQKAELEKVQ SKLSQYEGEI QLVPEELEFP HGLQVGAFKN ELENFKKNLE
KFKARKDNES YEADNLSEEH MAELGSFTGD EDILAKYLVS TERQEHSVVS NDSELFEIEE
SRFELDSNNF SEPNVNSRAD TLSFGPDKQM CSYNLLQATS EDAELEAKTF ASFLSDSSLP
QDKVGDGNEE KDEEKTRLIE RCVELIKQLR EKELALNRSH QETQEAIEKW EKTKMDLSFT
HLELEKEHEV RLCCEKELDE KTKKEKELEN KLNFLEKQRE DRDIIVCVEE LEFVTQASKS
LTWQEMVEDL KQEKETLIMQ LRAQEQLVKE VQEQKTASDS VTSEVQSLFG RQLAVLQHQR
DQMQIQLDAQ KAKNQTIAEL LGQKAILEET LLKEQDTLKS EINHKEQSLT DLLKEKTILE
ERLFAVGQEL IKAEKALEES ANNLENLETN VCKLNMKIRN LEKAQDCERL EYEEKLISTK
LEIQRLNAEV EAKNTEYIQK EKNLTDEMAY LKNCHLDRET CLQEALQKSE QAIQEVQSEM
KKHYEMEISK IESQHFSETT NLSLAHQKEI EKLYAEIREK VEKQQKLEEE RKEQIALIKK
VHEREHDREI AELIAKHDSE MKELRAMLSE EQQQVLDELQ QQMEAGHQVE IQHAQLQSQT
LYNLELEALR LSLSNMHTSQ LELIQSNLRK EKETALMELR EMLNDKRAQE IAILQSRHQF
ELEHIKEHNQ KEKEEIELKH QDELVDLRKN IELEMEEKHI QTLETLKGDW AVEAEMCLKM
VCEELSEKHQ TELDELQKAL KAELQKVKEE LKSLSLEKDQ VETKYKDLEN QHELAIIRLR
EQIQTEYDQC LEDMKRKSNE REQEIQQQLE KLQSTHTELK VQSQQEIKQL WSQLDSTRAS
RQELSELKEQ LLARTSHVEE IECLKHEFEQ HQQQQRSEHE TELEQLRIYF EKKLRAAEEN
YREELALLHQ RLQEVKEYSL MESETSQDQL VDISSSIISL EEAAEKERRD VFCQLNQQLE
QHKEELTCLR LQLDEQQRND LHSLRSSLTL QYKEDLMKMK MDLSDRYISE IEELKKKHCL
DLEQLRAKLS EEHIKEITKL RLQSAQDAAR QVEAEVAERI SVLEKEHRDK LSLLQSEKQY
IEELQEERQR LKKEISELKH IGMQHEMHMK EEMEKVKCKL LEDHNNELKK AKEEVQKMEQ
IHKEKEEEWK CESELVQIKT EEKLSLMCRE LEDKAECERL ALQKEFELHE AEMNLLRDEQ
AARIVELEKS LKEQQNSLRQ LEDSLANEQA THKSQAEYDS ELQAAKAVMA KELEKATLDL
QEECAAKLTE AQNKFMEEHK AMTQTFTTEQ EILLQELKGK HINELELQSQ QLQEKQKQQI
LSLAAELQTK HQTETEALKS TLQSKQQALL EAHVAELQTK HQAQIDELEA KHLSNLDSLE
SSYLSEIQNI RDEHKKILEE LQVHHREQLH QKDKENQVLL AEEKERLKLK HSEELLLSHE
NLKIELATLH IEKLKAMGAE LEVVHKEELN TALQNQRCLL EEENRKALDA LREEVLIMEE
HHKKALQELQ DLHVTEIQKQ KEEYSQQLKK EVKKLEVQHE HEQEMYASAS ASEVQTVRTA
LLAQFEEAKM KQQLQFQEEI ELLKCQSEVL LEQQITQLKE EFEAEKKAAL HNKEDVLVQE
AEEARALCRK EIEALSVQLQ EKTNKIIQLE KKVQSLSNET EETNSELETL LWRRDRENQE
GENLVAMLRS DIDLCQNERQ KMQDSYQRLL KSFMETVKAI IATEDLICKK IGICLDDSLA
SGDSRESRSL MEEMGFMQHF KTKEKHDMEK SELLDVTLTE HNQVSAVTDE GSELSQYLCE
SIFANPDLAF ENEEMIPKFC HRLRTAVEKL LELVTESTKQ LEKTHEIHAQ FEEEFSRRNQ
ETAQVVGQHQ ELMECLNEES EAKNQLALKL HKAEGLLKEV EFLAKEKVEL QCQAEKDYSS
LRSQMRVLEV ELEEQMNHNQ ELEKKLLEVT DLKQQIQVLE KQLKNQRQFM DEQAIEREHE
RDEFQQEIQK LEEQLKLAAK LQMSVEPREH GSYELSLQVE SLQSEIKEKM DDYNKLLLEK
EQKHQEVTIR DKEMETMAER IREMEHTNTD VSKIVSRLEQ ELQRMKKMET ELKQDKEALQ
QQQYNNLIQI SALQSKLDEA RHRVPTEGNT DHVLKEQLEA EKEALLTKER QVVSLLEQVE
EFKENLINKN DEILQLTLEL EMQKNLSTTS ISQLQLENAH LKEDIAKLSM KQSQILDYSE
SSVLQFPQAL LEEKNQEIDH LNEQVMRLQN ELENATDNKV VEDRKSEIKE LESLIEHLRG
DQERLRKDKE EEIEQLHGVI EKLQKELAHL GPVCHEISDS QDDLNDLGLE DQGENLQKEL
KKGSLDMKED TDQNKKNVLL DSKVKELQEE LELVSTAREA LQQLLEERES QFKMEVEILE
QNIQNVQESS RQHFKELTSL KIQYEAFQEE YNLIRTHLSQ RDVEVRKISS RIQELEDTLR
AREANLLERD LQIKTMAEQR VVETTELHHL TEKVVELEAE LEKRDDCQQS QAIEVQALQS
EVSRLGLTVQ TLNQKVVVYQ KEMDELQLSD TKLKDQIQEY LQQIEALLSE RDELYSQLES
YREKEQSNNQ EAKLPKLVSK QEREVLTRTK GMERLEEDWR TDVDQSFAAT VSPNNKLILI
EEQLDTTNSL QNEDDIIAKM TSHQEELKSE LPWVTEDLEV SEERPGSTLE DVKEKDAELT
VHSRNLKTQV KQLQETLLIQ EEEMTNKAEK LQGLKKHCQQ ILGFHQTTNP LKCNFSKKQE
HIKEMPQNFK DLITDMALWD SPEIVRKQDT STDLQLTLHL TPFSEVDSIH SMDLETMHTR
SSAVQGDTSG LFGYPKLAAY SNEETTDKLD LKSPCFSEST YSIAEYQDME KRILVREVDN
LTLTPSDSQD DVRSTVSGLE RASNGYSSIA QQEIACLGDG WGLDQMTIEV PSKPMILLCD
VLLDLFSDSS SDLAAKLNQE LETTEHLDAS VLAYLQYCGM FPDRMDSVKE KEILSPQLKT
VLKMVYEESR KILALSEYPF VLRDPKSVQQ PTAAEGWQKE GLTLLDAIQS LKDYLSKMTD
KGGKEYSDAC LDWRGELLQA VQSVLEKERN MLQLDLQSHL CNPGSGDKGS LVEKLEHIMK
QQEEQQQLVL EHLLSSDRSS LLSEIQDLRA QLRMTHLQNQ EKLQQLQEII TNAEDRGSKQ
EHQLRRKVEL LEYKIXXXXX XXXXXXQNSL SIEQQKASEM RELLKQEQTA ASNLKSELYE
SRLENEKLQK SLQDLRREIN QFRCELENRE KDLTGALQDL QNERLKEKEL QNVFEEQQLQ
HKRRADEKAK ELEELRATLK LQCIQNNQLS VALEHEQTAN DNLRKELQIE HSRCEALLSQ
ERTKLSELQR NLEVERNRSL ELLNSLNHER ILTEQLSVRA KEGVSCPHKE SLLEQTFVRD
LQVQLDEERS RAKELAAIIE KTHQQAICSK RQLEAEVQMC CEETQKEREI SNKLRATLES
LQSKKQEVIR SLEVQREREG KLKADQEELQ SRFKAMKEQE KNKKEERDKE RRWEQQSEVE
KQKEWQKDRE RLHELELQHQ RDECRIKELQ QTLADLEEQE RKLTSQESHQ EVSCPIKNDC
NIKLAFTTET ETLHLRQQLE KIRQQLLFVA VHLNEFIYKT VDKTVNDWSA SNNEAIASLL
HTLKELKSEL LTSSTHLNPS QDPVSLVDVL LKENGELTKS VTALTDEKLE LRAAVSRLEK
KLQQHLHRGN GNGQIRSMED ADSVQGLERA AWQREKTVLQ NALKQAESEL AKNTVEIENK
PVMEASNAKL QRLYKKYLRS ESFRKALVYQ KKYLLLLLGG FQDCEQATLS LIARMGVFPS
PADLQVSESH SRPFTKFRSA VRVVIAISRL KFLVKKWNKI NRKGIQGEVI SHGTGHNSVS
GARTEVLRQQ LPTINTNSPP TRDTGLCHKT SSARCISQSH RSSTWLCNRS HPSTSSVSEK
SLVSSTQDPE RSLSEYIHHL EVIQQRLGGV QPETRIGHRI PLGESQCHMQ RKSSRITSPE
KH
//
