ID   A0A3Q0GGH5_ALLSI        Unreviewed;      1073 AA.
AC   A0A3Q0GGH5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Cullin-associated NEDD8-dissociated protein 1 {ECO:0000256|ARBA:ARBA00040131};
DE   AltName: Full=Cullin-associated and neddylation-dissociated protein 1 {ECO:0000256|ARBA:ARBA00042178};
GN   Name=CAND1 {ECO:0000313|RefSeq:XP_025058592.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025058592.1};
RN   [1] {ECO:0000313|RefSeq:XP_025058592.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CAND family.
CC       {ECO:0000256|ARBA:ARBA00007657}.
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DR   RefSeq; XP_025058592.1; XM_025202807.1.
DR   AlphaFoldDB; A0A3Q0GGH5; -.
DR   Proteomes; UP000189705; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0010265; P:SCF complex assembly; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039852; CAND1/CAND2.
DR   InterPro; IPR013932; TATA-bd_TIP120.
DR   PANTHER; PTHR12696:SF1; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12696; TIP120; 1.
DR   Pfam; PF08623; TIP120; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          883..1045
FT                   /note="TATA-binding protein interacting (TIP20)"
FT                   /evidence="ECO:0000259|Pfam:PF08623"
FT   REGION          158..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..185
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1073 AA;  119116 MW;  CFDCF75705FAB88C CRC64;
     MADMLSRQGG LLVNFHPSIL TCLLPQLTSP RLAVRKRTII ALGHLVMSCG NIVFVDLIEH
     LLTELSKNDS MSTTRTYIQC IAAISRQAGH RIGEYLEKII PLVVKFCNVD DDELREYCIQ
     AFESFVRRCP KEVYPHVSTI INICLKYLTY DPNYNYDDED EDENAMDADG GDDDDQGSDD
     EYSDDDDMSW KVRRAAAKCL DAVVSTRHEM LPEFYKTVSP ALIARFKERE ENVKADVFHA
     YLSLLKQTRP VQSWLCDPDA MEQGETPLTM LQSQVPNIVK ALHKQMKEKS VKTRQCCFNM
     LTELVNVLPG ALTQHVPVLV PGIIFSLNDK SSSSNLKIDA LSCLYVILCN HSPQVFHPHV
     QALVPPVVAC VGDPFYKITS EALLVTQQLV KVIRPLDQPS SFDATPYIKD LFTCTIKRLK
     AADIDQEVKE RAISCMGQII CSLGDNLGTD LPNTLQIFLE RLKNEITRLT TVKALTLIAG
     SPLKIDLRPV LGEGVPILAS FLRKNQRALK LGTLSALDIL IKNYSDSLTA AMIDAVLDEL
     PPLISESDMH VSQMAISFLT TLAKVYPSSL SKISGSILNE LIGLVRSPLL QGGALSAMLE
     FFQALVVTGT NNLGYMDLLR MLTGPVYSQS TALTHKQSYY SIAKCVAALT RACPKEGPAV
     VGQFIQDVKN SRSTDSIRLL ALLSLGEVGH HIDLSGQIEL KSVILEAFSS PSEEVKSAAS
     YALGSISVGN LPEYLPFVLQ EITSQPKRQY LLLHSLKEII SSASVVGLKP YVENIWALLL
     KHCECAEEGT RNVVAECLGK LTLIDPETLL PRLKGYLASG SSYARSSVVT AVKFTISDHP
     QPIDPLLKNC IGDFLKTLED PDLNVRRVAL VTFNSAAHNK PSLIRDLLDT VLPHLYNETK
     VRKELIREVE MGPFKHTVDD GLDIRKAAFE CMYTLLDSCL DRLDIFEFLN HVEDGLKDHY
     DIKMLTFLML VRLSTLCPSA VLQRLDRLVE PLRATCTTKV KANSVKQEFE KQDELKRSAM
     RAVAALLTIP EAEKSPLMSE FQSQISSNPE LAAIFESIQK DSSSTNLESM DTS
//