ID A0A3Q0GIH0_ALLSI Unreviewed; 3785 AA.
AC A0A3Q0GIH0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Pericentrin isoform X7 {ECO:0000313|RefSeq:XP_025057983.1};
GN Name=PCNT {ECO:0000313|RefSeq:XP_025057983.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025057983.1};
RN [1] {ECO:0000313|RefSeq:XP_025057983.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR RefSeq; XP_025057983.1; XM_025202198.1.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR028745; AKAP9/Pericentrin.
DR InterPro; IPR019528; PACT_domain.
DR PANTHER; PTHR44981:SF3; PERICENTRIN; 1.
DR PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR Pfam; PF10495; PACT_coil_coil; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT DOMAIN 3559..3640
FT /note="Pericentrin/AKAP-450 centrosomal targeting"
FT /evidence="ECO:0000259|Pfam:PF10495"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3266..3292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3759..3785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 111..145
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 170..296
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 437..633
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 723..863
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1181..1260
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1303..1381
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1612..1653
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1681..1868
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1901..2069
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2127..2179
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2278..2347
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2466..2493
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2919..3148
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3181..3208
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3464..3539
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3785 AA; 441586 MW; 4D50DB1B5D84FC8E CRC64;
MEDEERQRKL EAGRAKLAHF RQRKTKSENT QSQKKAAKRK GSSIHTHDIP KEECTLVAQV
SDFLSDLGMS MESQTEDPDV SEASFEAKGD SDLPDPDVLD NHAVEELETA VQERNKIITR
LTSNLQQAQQ NQDDIQEETS LLTDQIHGLQ LQLLEADLLL KNKIPGKNEL AQAQQQMAVF
QNRLKEQSEH LQILHQKAHD LEVELESSQK NTKDKENLLA QMEENLKSTV QQLHKNIEEK
EETIKRLQDT VTSEKVHERE HDREIAELIA KHDSEMKELR AMLSEEQQQV LDELQQQMEA
GHQVEIQHAQ LQSQTLYNLE LEALRLSLSN MHTSQLELIQ SNLRKEKETA LMELREMLND
KRAQEIAILQ SRHQFELEHI KEHNQKEKEE IELKHQDELV DLRKNIELEM EEKHIQTLET
LKGDWAVEAE MCLKMVCEEL SEKHQTELDE LQKALKAELQ KVKEELKSLS LEKDQVETKY
KDLENQHELA IIRLREQIQT EYDQCLEDMK RKSNEREQEI QQQLEKLQST HTELKVQSQQ
EIKQLWSQLD STRASRQELS ELKEQLLART SHVEEIECLK HEFEQHQQQQ RSEHETELEQ
LRIYFEKKLR AAEENYREEL ALLHQRLQEV KEYSLMESET SQDQLVDISS SIISLEEAAE
KERRDVFCQL NQQLEQHKEE LTCLRLQLDE QQRNDLHSLR SSLTLQYKED LMKMKMDLSD
RYISEIEELK KKHCLDLEQL RAKLSEEHIK EITKLRLQSA QDAARQVEAE VAERISVLEK
EHRDKLSLLQ SEKQYIEELQ EERQRLKKEI SELKHIGMQH EMHMKEEMEK VKCKLLEDHN
NELKKAKEEV QKMEQIHKEK EEEWKCESEL VQIKTEEKLS LMCRELEDKA ECERLALQKE
FELHEAEMNL LRDEQAARIV ELEKSLKEQQ NSLRQLEDSL ANEQATHKSQ AEYDSELQAA
KAVMAKELEK ATLDLQEECA AKLTEAQNKF MEEHKAMTQT FTTEQEILLQ ELKGKHINEL
ELQSQQLQEK QKQQILSLAA ELQTKHQTET EALKSTLQSK QQALLEAHVA ELQTKHQAQI
DELEAKHLSN LDSLESSYLS EIQNIRDEHK KILEELQVHH REQLHQKDKE NQVLLAEEKE
RLKLKHSEEL LLSHENLKIE LATLHIEKLK AMGAELEVVH KEELNTALQN QRCLLEEENR
KALDALREEV LIMEEHHKKA LQELQDLHVT EIQKQKEEYS QQLKKEVKKL EVQHEHEQEM
YASASASEVQ TVRTALLAQF EEAKMKQQLQ FQEEIELLKC QSEVLLEQQI TQLKEEFEAE
KKAALHNKED VLVQEAEEAR ALCRKEIEAL SVQLQEKTNK IIQLEKKVQS LSNETEETNS
ELETLLWRRD RENQEGENLV AMLRSDIDLC QNERQKMQDS YQRLLKSFME TVKAIIATED
LICKKIGICL DDSLASGDSR ESRSLMEEMG FMQHFKTKEK HDMEKSELLD VTLTEHNQVS
AVTDEGSELS QYLCESIFAN PDLAFENEEM IPKFCHRLRT AVEKLLELVT ESTKQLEKTH
EIHAQFEEEF SRRNQETAQV VGQHQELMEC LNEESEAKNQ LALKLHKAEG IIEGYVAEKA
ALEEALNLKE ESERRLVVEL ENLRERFQEL TQEQAILGLL KEVEFLAKEK VELQCQAEKD
YSSLRSQMRV LEVELEEQMN HNQELEKKLL EVTDLKQQIQ VLEKQLKNQR QFMDEQAIER
EHERDEFQQE IQKLEEQLKL AAKLQMSVEP REHGSYELSL QVESLQSEIK EKMDDYNKLL
LEKEQKHQEV TIRDKEMETM AERIREMEHT NTDVSKIVSR LEQELQRMKK METELKQDKE
ALQQQQYNNL IQISALQSKL DEARHRVPTE GNTDHVLKEQ LEAEKEALLT KERQVVSLLE
QVEEFKENLI NKNDEILQLT LELEMQKNLS TTSISQLQLE NAHLKEDIAK LSMKQSQILD
YSESSVLQFP QALLEEKNQE IDHLNEQVMR LQNELENATD NKVVEDRKSE IKELESLIEH
LRGDQERLRK DKEEEIEQLH GVIEKLQKEL AHLGPVCHEI SDSQDDLNDL GLEDQGENLQ
KELKKGSLDM KEDTDQNKKN VLLDSKVKEL QEELELVSTA REALQQLLEE RESQFKMEVE
ILEQNIQNVQ ESSRQHFKEL TSLKIQYEAF QEEYNLIRTH LSQRDVEVRK ISSRIQELED
TLRAREANLL ERDLQIKTMA EQRVVETTEL HHLTEKVVEL EAELEKRDDC QQSQAIEVQA
LQSEVSRLGL TVQTLNQKVV VYQKEMDELQ LSDTKLKDQI QEYLQQIEAL LSERDELYSQ
LESYREKEQS NNQEAKLPKL VSKQEREVLT RTKGMERLEE DWRTDVDQSF AATVSPNNKL
ILIEEQLDTT NSLQNEDDII AKMTSHQEEL KSELPWVTED LEVSEERPGS TLEDVKEKDA
ELTVHSRNLK TQVKQLQETL LIQEEEMTNK AEKLQGLKKH CQQILGFHQT TNPLKCNFSK
KQEHIKEMPQ NFKDLITDMA LWDSPEIVRK QDTSTDLQLT LHLTPFSEVD SIHSMDLETM
HTRSSAVQGD TSGLFGYPKL AAYSNEETTD KLDLKSPCFS ESTYSIAEYQ DMEKRILVRE
VDNLTLTPSD SQDDVRSTVS GLERASNGYS SIAQQEIACL GDGWGLDQMT IEVPSKPMIL
LCDVLLDLFS DSSSDLAAKL NQELETTEHL DASVLAYLQY CGMFPDRMDS VKEKEILSPQ
LKTVLKMVYE ESRKILALSE YPFVLRDPKS VQQPTAAEGW QKEGLTLLDA IQSLKDYLSK
MTDKGGKEYS DACLDWRGEL LQAVQSVLEK ERNMLQLDLQ SHLCNPGSGD KGSLVEKLEH
IMKQQEEQQQ LVLEHLLSSD RSSLLSEIQD LRAQLRMTHL QNQEKLQQLQ EIITNAEDRG
SKQEHQLRRK VELLEYKIXX XXXXXXXXXQ NSLSIEQQKA SEMRELLKQE QTAASNLKSE
LYESRLENEK LQKSLQDLRR EINQFRCELE NREKDLTGAL QDLQNERLKE KELQNVFEEQ
QLQHKRRADE KAKELEELRA TLKLQCIQNN QLSVALEHEQ TANDNLRKEL QIEHSRCEAL
LSQERTKLSE LQRNLEVERN RSLELLNSLN HERILTEQLS VRAKEGVSCP HKESLLEQTF
VRDLQVQLDE ERSRAKELAA IIEKTHQQAI CSKRQLEAEV QMCCEETQKE REISNKLRAT
LESLQSKKQE VIRSLEVQRE REGKLKADQE ELQSRFKAMK EQEKNKKEER DKERRWEQQS
EVEKQKEWQK DRERLHELEL QHQRDECRIK ELQQTLADLE EQERKLTSQE SHQEVSCPIK
NDCNIKLAFT TETETLHLRQ QLEKIRQQLL FVAVHLNEFI YKTVDKTVND WSASNNEAIA
SLLHTLKELK SELLTSSTHL NPSQDPVSLV DVLLKENGEL TKSVTALTDE KLELRAAVSR
LEKKLQQHLH RGNGNGQIRS MEDADSVQGL ERAAWQREKT VLQNALKQAE SELAKNTVEI
ENKPVMEASN AKLQRLYKKY LRSESFRKAL VYQKKYLLLL LGGFQDCEQA TLSLIARMGV
FPSPADLQVS ESHSRPFTKF RSAVRVVIAI SRLKFLVKKW NKINRKGIQG EVISHGTGHN
SVSGARTEVL RQQLPTINTN SPPTRDTGLC HKTSSARCIS QSHRSSTWLC NRSHPSTSSV
SEKSLVSSTQ DPERSLSEYI HHLEVIQQRL GGVQPETRIG HRIPLGESQC HMQRKSSRIT
SPEKH
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