ID   A0A3Q0GIY6_ALLSI        Unreviewed;       895 AA.
AC   A0A3Q0GIY6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Polyhomeotic-like protein 2 isoform X3 {ECO:0000313|RefSeq:XP_025059427.1};
GN   Name=PHC2 {ECO:0000313|RefSeq:XP_025059427.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025059427.1};
RN   [1] {ECO:0000313|RefSeq:XP_025059427.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_025059427.1; XM_025203642.1.
DR   AlphaFoldDB; A0A3Q0GIY6; -.
DR   Proteomes; UP000189705; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09577; SAM_Ph1_2_3; 1.
DR   Gene3D; 3.30.60.160; -; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR012313; Znf_FCS.
DR   InterPro; IPR038603; Znf_FCS_sf.
DR   PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR   PANTHER; PTHR12247:SF86; POLYHOMEOTIC-LIKE PROTEIN 2; 1.
DR   Pfam; PF16616; PHC2_SAM_assoc; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   Pfam; PF21319; zf-FCS_1; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
DR   PROSITE; PS51024; ZF_FCS; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00367}.
FT   DOMAIN          660..694
FT                   /note="FCS-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51024"
FT   DOMAIN          831..895
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          107..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          359..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          511..588
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          640..662
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          709..750
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          765..803
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        264..296
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..383
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..433
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        553..584
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        732..750
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        765..792
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   895 AA;  94762 MW;  4DA1318F17A042EA CRC64;
     MENEQLQVPP PSSSSASTST TTSSSSNGRQ PGPQISVYSG IPDRQTVQVI QQALHRQPNT
     AAQYLQQMYA AQQQHLMLQT AALQQQHLSS AQLQSLAAVQ QASLAANRQG GSSGSNASQQ
     APSQQPTINL ATSPAAAQLI NRAQSVNSAA AAASGITQQA VLLGNAASPA LTASQAQMYL
     RAQMAQQSNL VQVARSLGRA VPLSPQLIFT PTATVATVQP ESGAGPTSQP STTTAQVQNL
     AIRTQQTVAQ GVASSQAQQL PTLAMKPAPG SSQPASSASQ GKAAAQAPTM GSKGGQAEQV
     TEHLKKGDSV PSSADSRGHP MNRTVTPVTS HPLIAPAYAQ LQPHQLLQQQ KQIQHQFVIQ
     QQQIQPRPQP QLIQGGASTS PQLQPLPSPT PSLAVQPSPQ AQVQLQGHGA PQAQASLPHP
     QPCQASSQHK PGTSQPCPPT PHISGLQAVG PAPPGAEGGT QNGHPGCLNH AAPRKFQHAS
     AVILQLQPAV GTPQLGIAEN SRKDILPADK SSESLPAQQQ QAAAPTPPAV APAPEDTECR
     RPPAPEPGQD RVHAQSDPSS PGMTSGNGNS SSTVAGTAPQ NGENKPPQAI VKPQILTHVI
     EGFVIQEGAE PFPVGRSSLL VGNLKKKYAQ GLLAEKLPQQ DNTTTTDSEM EEPYVQESKE
     EGTPPKLKCE LCGRVDFAYK FKRSKRFCSM ACAKRYNVGC TKRVGLFHPD RSKLQKPGGP
     PHGRRRTCKS ALPTLSKDTK KQTPVSLSTG SVPLSVTASL QLNHAQEDSS RCSDNSSYEE
     PLSPVSASSS ASRRRQGERD MELRDMELPD MHMRDLVGIG HHFLPSEPTK WNVEDVYEFI
     RSLPGCQEIA EEFRAQEIDG QALLLLKEDH LMSAMNIKLG PALKIYARIS MLKDS
//