ID A0A3Q0GJK1_ALLSI Unreviewed; 2044 AA.
AC A0A3Q0GJK1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Ankyrin-3 isoform X10 {ECO:0000313|RefSeq:XP_025058388.1};
GN Name=ANK3 {ECO:0000313|RefSeq:XP_025058388.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025058388.1};
RN [1] {ECO:0000313|RefSeq:XP_025058388.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR RefSeq; XP_025058388.1; XM_025202603.1.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08803; Death_ank3; 1.
DR Gene3D; 2.60.220.30; -; 2.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 4.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR037971; Ank3_Death.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24198:SF173; ANKYRIN-3; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 7.
DR Pfam; PF13637; Ank_4; 2.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 22.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 21.
DR PROSITE; PS50088; ANK_REPEAT; 21.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 56..88
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 89..121
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 122..154
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 155..178
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 225..257
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 258..290
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 291..323
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 324..356
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 357..389
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 390..422
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 423..455
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 456..488
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 489..521
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 522..554
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 555..587
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 588..620
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 621..653
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 654..686
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 687..719
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 720..752
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 753..785
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 991..1146
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1148..1295
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1481..1565
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1707..1741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1781..1961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1721..1741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1781..1796
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1838..1896
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1925..1961
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2044 AA; 224737 MW; BE601D15218C64D5 CRC64;
MSEEAKERNA KPAHRKKKGK KSDTNASYLR AARAGNLEKA LDYLKSGVDI NICNQNGLNA
LHLASKEGHV EVVSELIQRG ANVDAATKKG NTALHIASLA GQTEVVKVLV ANAANVNAQS
QNGFTPLYMA AQENHLEVVK FLLDNGASQS LATEDGFTPL AVALQQGHDQ VVSLLLENDT
KGKVRLPALH IAARKDDTKA AALLLQNDHN ADVESKMMVN RTTESGFTPL HIAAHYGNIN
VATLLLNRGA AVDFTARNDI TPLHVASKRG NANMVKLLLD RGAKIDAKTR DGLTPLHCGA
RSGHEQVVEM LLDRGAPILS KTKNGLSPLH MATQGDHLNC VQLLIQHNVP VDDVTNDYLT
ALHVAAHCGH YKVAKVLLDK TANPNAKALN GFTPLHIACK KNRIKVMELL LKHGASIQAV
TESGLTPIHV AAFMGHVNIV SQLMHHGASP NTTNVRGETA LHMAARAGQT EVVRYLIQNG
AQVEAKAKDD QTPLHISARL GKADIVQQLL QQGASPNATT TSGYTPLHLS AREGHEDVAL
VLLDHGASLA IITKKGFTPL HVASKYGKIE VANLLLQKNA SPDAAGKSGL TPLHVAAHYD
NQKVALLLLD QGASPHASAK NGYTPLHIAA KKNQMDIATT LLEYGADANA VTRQGIAPVH
LAAQEGHVDM VSLLLTRNAN MNLSNKSGLT PLHLAAQEDR VNVAEVLVNQ GAVTDAQTKM
GYTPLHVGCH YGNIKIVNFL LQHFAKVNAK TKNGYTPLHQ AAQQGHTHII NVLLQHGASP
NELTVNGNTA LAIAKRLGYI SVVDTLKVVT EETMTTITVT EKHKMNVPET MNEVLDMSDD
EAVRKANVPE ILSDGEYISD VEEGEDAMTG DTDKYLGPQD LKELGDDSLP AEGYMGFSLG
ARSASPKVSL RSFSSDRSYT LNRSSYARDS MMIEELLVPP KDQHLSFPRE FDSDSLRHYS
WAADTLDNVN LVSSPIHSGY SSPLPQYDSS FLVSFMVDAR GGSMRGSRHH GMRIIIPPRK
CTAPTRITCR LVKRHKLASP PPMVEGEGLA SRLVEMGPAG AQFLGPVIVE IPHFGSMRGK
ERELIVLRSE NGETWKEHQY DSKHEGLNEI LNGMDEELDS AEELEKKRIC RIITKDFPQY
FAVVSRIKQE SNQIGPEGGV LSSTTVPRVQ ASFPEGALTK RIRVGLQAQP VPDEIVKKIL
GNKATFSPIV TVEPRRRKFH KPITMTIPVP PPSGEGVTNG YKGDTTPSLR LLCSITGGTS
PAQWEDITGT TPLTFINDCV SFTTNVSARF WLADCHQLLE TVGLATQLYR ELICVPYMAK
FVIFAKMNDP VESNLRCFCM TDDKVDKTLE QQENFEEVAR SKDIEVLEGK PIYVDCYGNL
APLTKGGQQL VFNFYAFKEN RLPFSIKIRD TSQEPCGRLS FLKEPKTTRG LPQTAVCNLN
ITLPAHKKET ESDQDDETEK ADRRQNFVSL ALRPQSPCER TDIRMAIVAD HLGLSWTELA
RELNFSVDEI NQIRVENPNS LIAQSFMLLK KWVTRDGKNA TTDALTTVLT KINRIDIVTL
LEGPIFDYGN ISGTRSFADE NNVFHDPIDG YPTIQVELET PTGLRFVPPT PFQQDDFFSN
ISSIESPLRT PSRLSDVLVT SQENIDGTVT GPPVVTEEDT TLEDSKFNFS VPREGTVKNI
STGQSQLEDL DDYPRYLGIY AGMTKDDKYS KQMQGEEPSQ RGVRIEQHER EKSGTDEEMT
EEKLKSLFED IHLEEGVESE EMTEEKVWAI LKDVQQAEQE MSSITGWQSE PSSVNVEPPT
PGRRISGELL DRLDDSLDQN RDSVPSYLKG EAGKLEANGS HTESTTNAKT KSYVQESVNG
VGKQSNKETL KPKPQSSVCV EKQTLPSTTQ QKSLEEASKL AVEEPKISMP VGMKMSWTTS
EDGKMRPSIQ EEEGAVMSEQ KEFSDSDIEV QSESSSDEEQ RITTRVYRRR LILKGEEAKN
IPGESVTEEQ FTDEEGNVIT RKVTRKVVRR VVIPHEKRVG AMQGEGYKVK TKKEVRHVEK
KSYS
//
