ID A0A3Q0GLR0_ALLSI Unreviewed; 1184 AA.
AC A0A3Q0GLR0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Myelin transcription factor 1-like protein isoform X2 {ECO:0000313|RefSeq:XP_025059173.1};
GN Name=MYT1L {ECO:0000313|RefSeq:XP_025059173.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025059173.1};
RN [1] {ECO:0000313|RefSeq:XP_025059173.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
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DR RefSeq; XP_025059173.1; XM_025203388.1.
DR AlphaFoldDB; A0A3Q0GLR0; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 6.
DR InterPro; IPR013681; Myelin_TF.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816:SF11; MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN; 1.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR Pfam; PF08474; MYT1; 1.
DR Pfam; PF01530; zf-C2HC; 6.
DR SUPFAM; SSF103637; CCHHC domain; 6.
DR PROSITE; PS51802; ZF_CCHHC; 6.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT DOMAIN 621..870
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT REGION 56..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1056..1125
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 90..170
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1184 AA; 133383 MW; AAF17A888FBB63AF CRC64;
MEVDADEKRH RTRSKGVRVP VEPAIQELFS CPTPGCDGSG HVSGKYARHR SVYGCPLAKK
RKTQDKQPQE PAPKRKPFVV KTDNSSVDEC YETDGTEEMD EKEEEEEEEE EEEYSDVNEE
QVDDDEDDEE IDREEDEEIE EEEEDEEEGE DVEDEEEEEE EEEEEEEEER EDHQMNCHNT
RIMQDTEKDD NNNDEYDNYD ELVAKSLLNL GKIAEDAAYR ARTESEMNSN TSNSLEDDSD
KNENIGRKSE LSLDLDSDVV RETVDSLKLL AQGHGVVLSE NINDRNYADN TSQQDNRNMN
FVMLGKPVNN GLAEKMVEES DEEVCLSSLE CLRNQCFDLA RKLSETNPQE RNQQQNMNTR
QHVRQEDDFQ GRTPDRNYSD MMNLMRLEEQ LSPRSRTFSS CAKEDGCHER DDDTTSITSD
RSEEVFDMTK GNLTLLEKAI ALETERAKAM REKMAVEAGR RDNMRSYEEQ SPRQLSGDDR
KPKSSDGHVK KPYYDPSRTE KKESKCPTPG CDGTGHVTGL YPHHRSLSGC PHKDRVPPEI
LAMHENVLKC PTPGCTGRGH VNSNRNSHRS LSGCPIAAAE KLAKAQEKHQ NCDVSKSNQA
SDRVLRPMCF VKQLEIPQYG YRNNVPTTTP RSNLAKELEK YSKTTFEYNS YDNHAYGKRA
IAPKVQSRDI SPKGYDAKRY CKNSSPTSST TSSYAPSSSS NMSCGGGSSA SSTCSKSSFD
YTHDMEAAHM AATAILNLST RCREMPQNLS TKPQDLCARN PDMEVDENGT LDLSMNKQRQ
RDGCCTILTP LEPMSPQRQA VMNNRCYQLN ESDCWDLPVD YTKMKPSRID EDDSKEINPE
DLDPFQEALE ERRYPGEVTI PSPKPKYPQC KESKKDLITL SGCPLADKSI RSMLATSSQE
LKCPTPGCDG SGHITGNYAS HRSLSGCPRA KKSGIRIAQS KEDKEDQEPI RCPVPGCDGQ
GHITGKYASH RSASGCPLAA KRQKDGYLNG SQFSWKSVKT EGMSCPTPGC DGSGHVSGSF
LTHRSLSGCP RATSAMKKAK LSGEQMLTIK QRASNGIEND EEIKQLDEEI KELNESNSQM
EADMIKLRTQ ITTMESNLKT IEEENKVIEQ QNESLLHELA NLSQSLIHSL ANIQLPHMEP
INEQNFDAYV TTLTDMYTNQ DRYQSPENKA LLENIKQAVR GIQV
//
