ID A0A3Q0GT38_ALLSI Unreviewed; 1435 AA.
AC A0A3Q0GT38;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Neogenin isoform X4 {ECO:0000313|RefSeq:XP_025062959.1};
GN Name=NEO1 {ECO:0000313|RefSeq:XP_025062959.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025062959.1};
RN [1] {ECO:0000313|RefSeq:XP_025062959.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. DCC family.
CC {ECO:0000256|ARBA:ARBA00009588}.
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DR RefSeq; XP_025062959.1; XM_025207174.1.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 6.
DR CDD; cd05722; IgI_1_Neogenin_like; 1.
DR CDD; cd05723; IgI_4_Neogenin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR010560; Neogenin_C.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF06583; Neogenin_C; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1081..1105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..136
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 141..227
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 235..325
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 330..415
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 430..524
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 530..620
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 625..719
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 729..820
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 844..940
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 945..1042
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1039..1074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1115..1137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1151..1183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1164..1183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1258..1327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1435 AA; 157998 MW; 9A5CA7456319ADF6 CRC64;
MALQARLDFA KLRFWWVPSD NFFKDSTYLI GKASSVRTFT PFYFVVEPTD TLSVRGASVV
LNCSAFCETS PKIEWKKDGT FLNLVSDDRR QLLPDGSLLI NSVVHSKHNK PDEGYYQCVA
TVESLGTIVS RTAKLTIAGL PKFISQPEST SVYRGNSAIL NCEVNADLVP FVRWEQARQP
LFLDDRVFKL PSGALIISNA TDGDEGLYRC IIESGGSPKY SDEAELKILP DPEFPSDLVF
LRQPSSLIRV TGQSAVLPCA AAGFPTPVIR WTRNEEELIT EGSERFLLLA GGSLEISDIM
EDDAGTYACI VDNGNETAEA QADLTVLAPP EFLKQPANIY AHESMDIVFE CEVTGKPTPT
VKWVKNGDMV IPSDYFKIVK EHNLQVLGLV KSDEGFYQCI AENDVGNVQA GAQLIILEHA
PATTGPLPSA PRDVVATLVS TRFIKLTWRT PASDPQGDNL TYSVFYTKEG INRERVENTS
RPGEMQVTIQ NLMPETVYIF RVVAQNKHGP GESSVPLKVA TQPEVQLPGP APNIRAYANS
PTSITVTWET PLSGNGEIQN YKLYYMEKGT DNEQDVDVGG HSYTINGLKK YREYSFRVVA
YNKHGPGVST QDVVVRTLSD VPSAPPQNLS LEVRNSKSIM VHWQPPPPGT HNGQITGYKI
RYRKVSRKSD VTESIGGTQI FQLIEGLERG TEYSFRVAAL TINGTGPATD WVSAETFESD
LDETRVPEVP SSLHVRPLVT SIVVSWTPPE NQNIVVRGYA IGYGVGSPHA QTIKVDYKQR
YYTIENLDPS SHYVITLKAF NNVGEGIPLY ESAVTRSQTD TSEVDVFVIN APYTPVPDPS
PMMPPVGVQA SILSHDTIRI TWADNSLPKN QKITDARYYT VRWKTNIPAN TKYKTANTTT
LSYLVTGLKP NTLYEFSVMV TKGRRSSTWS MTAHGTTFEL VPTSPPKDVT VVSKEGKPRT
IIVNWQPPSE ANGKITGYII YYSTDVNAEI HDWVIEPVVG NRLTHQIQEL TLDTPYYFKI
QARNSKGMGP MSEAVQFRTP KASGTGGKGS RPVDLGPDYK PPMSGSNSPH GSPTSPLDSN
MLLVIIVSVG VITIVIVVIV AVFCTRRTTS HQKKKRAACK SVNGSHKYKG NSKDVKPPDL
WIHHERLELK PIDKSPDPNP IMTDTPIPRN SQDITPVDNS MDSNIHQRRN SYRGHESEDS
MSTLAGRRGM RPKMMMPFDS QPPQPVISAH PIHSLDNPHH HFHSGSLASP TRSYLHHQVN
PWPIGTSMSH SDRANSTESV RNTPSTDTMP ASSSQTCADH QDPDSATGSY LASAQEEDSS
QNLPTAHVRP SHPLKSFAVP AVPPSSSTYD PALPSTPLLS QQASNHPVHS VKTASIGTLG
RTRPPMPVIV PSAPDVQETT RMLEDSESNY EPDELTKEMA HLEGLMKDLN AITTA
//
