ID A0A3Q0GT39_ALLSI Unreviewed; 1466 AA.
AC A0A3Q0GT39;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Neogenin isoform X1 {ECO:0000313|RefSeq:XP_025062956.1};
GN Name=NEO1 {ECO:0000313|RefSeq:XP_025062956.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025062956.1};
RN [1] {ECO:0000313|RefSeq:XP_025062956.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. DCC family.
CC {ECO:0000256|ARBA:ARBA00009588}.
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DR RefSeq; XP_025062956.1; XM_025207171.1.
DR STRING; 38654.A0A3Q0GT39; -.
DR KEGG; asn:102382885; -.
DR InParanoid; A0A3Q0GT39; -.
DR OrthoDB; 5398621at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 6.
DR CDD; cd05722; IgI_1_Neogenin_like; 1.
DR CDD; cd05723; IgI_4_Neogenin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR010560; Neogenin_C.
DR PANTHER; PTHR44170:SF14; NEOGENIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF06583; Neogenin_C; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1112..1136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..136
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 141..227
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 235..325
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 330..415
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 450..544
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 550..640
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 645..739
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 749..840
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 864..960
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 965..1062
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1049..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1182..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1289..1384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1195..1214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1289..1358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1466 AA; 161234 MW; 5C779F8E8C317EC5 CRC64;
MALQARLDFA KLRFWWVPSD NFFKDSTYLI GKASSVRTFT PFYFVVEPTD TLSVRGASVV
LNCSAFCETS PKIEWKKDGT FLNLVSDDRR QLLPDGSLLI NSVVHSKHNK PDEGYYQCVA
TVESLGTIVS RTAKLTIAGL PKFISQPEST SVYRGNSAIL NCEVNADLVP FVRWEQARQP
LFLDDRVFKL PSGALIISNA TDGDEGLYRC IIESGGSPKY SDEAELKILP DPEFPSDLVF
LRQPSSLIRV TGQSAVLPCA AAGFPTPVIR WTRNEEELIT EGSERFLLLA GGSLEISDIM
EDDAGTYACI VDNGNETAEA QADLTVLAPP EFLKQPANIY AHESMDIVFE CEVTGKPTPT
VKWVKNGDMV IPSDYFKIVK EHNLQVLGLV KSDEGFYQCI AENDVGNVQA GAQLIILEHD
VAIPTLPPTS LTSATTDHLA PATTGPLPSA PRDVVATLVS TRFIKLTWRT PASDPQGDNL
TYSVFYTKEG INRERVENTS RPGEMQVTIQ NLMPETVYIF RVVAQNKHGP GESSVPLKVA
TQPEVQLPGP APNIRAYANS PTSITVTWET PLSGNGEIQN YKLYYMEKGT DNEQDVDVGG
HSYTINGLKK YREYSFRVVA YNKHGPGVST QDVVVRTLSD VPSAPPQNLS LEVRNSKSIM
VHWQPPPPGT HNGQITGYKI RYRKVSRKSD VTESIGGTQI FQLIEGLERG TEYSFRVAAL
TINGTGPATD WVSAETFESD LDETRVPEVP SSLHVRPLVT SIVVSWTPPE NQNIVVRGYA
IGYGVGSPHA QTIKVDYKQR YYTIENLDPS SHYVITLKAF NNVGEGIPLY ESAVTRSQTD
TSEVDVFVIN APYTPVPDPS PMMPPVGVQA SILSHDTIRI TWADNSLPKN QKITDARYYT
VRWKTNIPAN TKYKTANTTT LSYLVTGLKP NTLYEFSVMV TKGRRSSTWS MTAHGTTFEL
VPTSPPKDVT VVSKEGKPRT IIVNWQPPSE ANGKITGYII YYSTDVNAEI HDWVIEPVVG
NRLTHQIQEL TLDTPYYFKI QARNSKGMGP MSEAVQFRTP KAESSDKMPN DQASGTGGKG
SRPVDLGPDY KPPMSGSNSP HGSPTSPLDS NMLLVIIVSV GVITIVIVVI VAVFCTRRTT
SHQKKKRAAC KSVNGSHKYK GNSKDVKPPD LWIHHERLEL KPIDKSPDPN PIMTDTPIPR
NSQDITPVDN SMDSNIHQRR NSYRGHESED SMSTLAGRRG MRPKMMMPFD SQPPQPVISA
HPIHSLDNPH HHFHSGSLAS PTRSYLHHQV NPWPIGTSMS HSDRANSTES VRNTPSTDTM
PASSSQTCAD HQDPDSATGS YLASAQEEDS SQNLPTAHVR PSHPLKSFAV PAVPPSSSTY
DPALPSTPLL SQQASNHPVH SVKTASIGTL GRTRPPMPVI VPSAPDVQET TRMLEDSESN
YEPDELTKEM AHLEGLMKDL NAITTA
//
