ID   A0A3Q0GYC5_ALLSI        Unreviewed;      2097 AA.
AC   A0A3Q0GYC5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Dedicator of cytokinesis protein 7 isoform X8 {ECO:0000313|RefSeq:XP_025064467.1};
GN   Name=DOCK7 {ECO:0000313|RefSeq:XP_025064467.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025064467.1};
RN   [1] {ECO:0000313|RefSeq:XP_025064467.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00983}.
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DR   RefSeq; XP_025064467.1; XM_025208682.1.
DR   Proteomes; UP000189705; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd08696; C2_Dock-C; 1.
DR   CDD; cd11703; DHR2_DOCK7; 1.
DR   Gene3D; 1.20.58.740; -; 1.
DR   Gene3D; 1.25.40.410; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR037808; C2_Dock-C.
DR   InterPro; IPR027007; C2_DOCK-type_domain.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR021816; DOCK_C/D_N.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF78; DEDICATOR OF CYTOKINESIS PROTEIN 7; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   Pfam; PF14429; DOCK-C2; 1.
DR   Pfam; PF11878; DOCK_C-D_N; 1.
DR   PROSITE; PS51650; C2_DOCK; 1.
DR   PROSITE; PS51651; DOCKER; 1.
PE   3: Inferred from homology;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT   DOMAIN          558..724
FT                   /note="C2 DOCK-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51650"
FT   DOMAIN          1635..2071
FT                   /note="DOCKER"
FT                   /evidence="ECO:0000259|PROSITE:PS51651"
FT   REGION          134..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          889..914
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..155
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        889..911
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2097 AA;  238075 MW;  D40A987FB4535004 CRC64;
     MFDPNTGTMR TVAAEVRKQI SGQYGGSPQL LKNLNIGGSV SHHTTVPLTE AVDPVDLEEY
     LITHPLAVDS GPLRDLLEFP QDDIEVVYTP RECRTLVSAV PEESEMDPHV RDCVRSYTED
     WAIVNRKYHK LGTGFNPNTL DKQKERQKGL PKQIFESDEA PDGNSYQDEQ DDLKRRSMSI
     DDTPRGSWAC SIFDLKNSLP DALLPNLLDR TPNEEIDHQN DDQRKSNRHK ELFALHPAPD
     EEEPIERLCV PEVPKEHFGQ RLLVKCLSLK FEIEIEPIFA SLALYDVKEK KKISENFYFD
     LNSEQMKAML RPHVPPAAIS TLARSAIFSI TYPSQDVFLV IKLEKVLQQG DIGECAEPYM
     IFKEADAAKN KEKLEKLKSQ SDQFCQRLGK YRMPFAWTAI HLMNIVSSAG SLERDSTEVE
     VGTGERKGSW SERRNSSIVG RRSLERTTSG DEACNLTSFR PATLTVTNFF KQEGDRLSDE
     DLYKFLADMR RPSSVLRRLR PITAQLKIDI SPAPENPHYC LTPELLQVKL YPDSRVRPTR
     EILEFPARDV YVPNTTYRNL LYVYPQSLNF ANRQGSARNI TVKVQFMYGE DPSNAMPVIF
     GKSSCPEFSK EAYTAVVYHN RSPDFHEEIK VKLPATLTDH HHLLFTFYHV SCQQKQNTPL
     ETPVGYTWIP MLQNGRLKTG QFCLPVSLEK PPQAYSVLSP EVPLPGMKWV DNHKGVFNVE
     VVAVSSIHTQ DPYLDKFFAL VHALDEHMFP VRIGDMRIME NNLENELKSS ISALNSSQLE
     PVVRFLHLLL DKLILLVVRP PVIAGQIVNL GQASFEAMAS IINRLHKNLD GNQDQHGRNS
     LLASYIYYVF RLPNTYPNSP SPGPGGLGGS MHYATMARSA VRPASLNLNR SRSLSNSNPD
     ISGTPTSPDD EVRSIIGSKA TDRSCNRMSS HTETSSFLQT LTGRLPTKKL FHEELALQWV
     VCSGSVREAA LQQAWFFFEL MVKSMVHHLY FADKLDAPRK NRFPERFMDD IAALVSTIAS
     DIVSRFQKDT EMVERLNTSL AFFLNDLLSI MDRGFVFSLV KAYYKQVSSK LYSLPNPSNL
     ASLRLDFLRI ICSHEHYVTL NLPCSLLTPP ASPSPSVSSA TSQSSGFSTN VQDQKIANMF
     ELSVPFRQQH YLAGLVLTEL AVILDPDADG LFGLHKKVIN MVHNLLSSHD SDPRYSDPQV
     KARVAMLYLP LIGVIMETVP QLYDFTETHN QRGRPSCVAV DDYESEGGSM ISQTVAMAIA
     GTTIPQLTRP SSFLLTSSTG RQHSTFSAES SRSLLICLLW VLKNADESVL QKWFTDLSVL
     QLNRLLDLLY LCVSCFEYKG KKVFERMNSL TFKKSKDMRA KLEEAILGSI GARQEMVRRS
     RGQLERSPSG SAFGSQENLR WRKDMTHWRQ NTEKLDKSRA EIEHEALIDG NLATEANLII
     LDTLEIVVQT VSVTESKESI LGGVLKVLLH SMACNQSALY LQHCFATQRA LVSKFPELLF
     EEETEQCADL CLRLLRHCSS SISTIRSHAS ASLYLLMRQN FEIGNNFARV KMQVTMSLSS
     LVGTSQNFNE EFLRRSLKTI LTYAEEDLEL RDTTFPDQVQ DLVFNLHMIL SDTVKMKEHQ
     EDPEMLIDLM YRIAKGYQNS PDLRLTWLQN MAGKHSERSN HAESAQCLVH SAALVAEYLS
     MLEDRKYLPV GCVTFQNISS NVLEESAVSD DVVSPDEEGI CSGKYFTEAG LVGLLEQAAA
     SFSMAGMYEA VNEVYKVLIP IHEANRDAKK LSTIHGKLQE AFSKIVHQST GWERMFGTYF
     RVGFYGTKFG DLDEQEFVYK EPAITKLAEI SHRLEGFYGE RFGEDVVEVI KDSNPVDKCK
     LDPNKAYIQI TYVEPYFDTY EMKDRITYFD KNYNLRRFMY CTPFTLDGRA HGELHEQFKR
     KTILTTSHAF PYIKTRINVI HKEEIILTPI EVAIEDMQKK TQELAFATHQ DPADPKMLQM
     VLQGSVGTTV NQGPLEVAQV FLSEIPNDPK LFRHHNKLRL CFKDFTKRCE DALRKNKSLI
     GPDQKEYQRE LERNYHRLKE ALQPLINRKI PQLYKAVLPV ACHRDSFSRM SLRKMDI
//