ID   A0A3Q0H0F2_ALLSI        Unreviewed;      1278 AA.
AC   A0A3Q0H0F2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=FH1/FH2 domain-containing protein 1 {ECO:0000313|RefSeq:XP_025065217.1};
GN   Name=FHOD1 {ECO:0000313|RefSeq:XP_025065217.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025065217.1};
RN   [1] {ECO:0000313|RefSeq:XP_025065217.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025065217.1; XM_025209432.1.
DR   AlphaFoldDB; A0A3Q0H0F2; -.
DR   STRING; 38654.A0A3Q0H0F2; -.
DR   KEGG; asn:102380570; -.
DR   InParanoid; A0A3Q0H0F2; -.
DR   OrthoDB; 2918313at2759; -.
DR   Proteomes; UP000189705; Unplaced.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR041387; FHOD1_GBD_N.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   PANTHER; PTHR45920:SF2; FH1_FH2 DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR   Pfam; PF02181; FH2; 1.
DR   Pfam; PF18382; Formin_GBD_N; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT   DOMAIN          8..390
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          739..1134
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          296..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          480..542
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          722..746
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1120..1260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        296..318
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..346
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..507
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        511..542
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        722..737
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1138..1211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|RefSeq:XP_025065217.1"
SQ   SEQUENCE   1278 AA;  141287 MW;  0B67260F33EFA46C CRC64;
     PALEAGTGRP GAGAVLPLGL GGGLEDCTLQ VSPSGHYLDL ELSLLEQKDE LEGFYEEASK
     GRRPTLIVRT QLSVRVQAIL EKLYNSQGPE LRRSLFSLKQ LFQEDKDLVP EFVNLEGLTC
     LIKVGAQADQ NYQNYILRAL SQIMLFVDGM QGVIDHNETV QWLYTLTGSL YRLVVKTALK
     LLLVFVEYTE SNAQLLIEAI NMVDQKRGAN PWSNLMAILE QRNGADTELL LFTIMLINKT
     LVALPDQDSF YDVTDCLEQQ GMESIMQQHM NSKGTDPDLK QQFAIYESAL RYEDGVEESP
     LGARKERRKT DEGRRGWRSL GGGIDVSFTA SSPSPVQESN RLAENSSTLI ESPAKDLHPP
     APSPPVEVVT ESSPAQPCFQ SVYNSASNVQ LSVPAVAGER EQPSIVGERS IYKLHHTTPI
     WQEENPPLHG DKPILRKFET RFLENLAASQ KEKISAMAKG QIDIFTEVAL GHTATVFPPG
     RDGSVCEPDT ELTATGRRSK MEEQNKAVNE MEPCSAKSTQ GRDEKQGNTS GPSLPWHEST
     ESCSTISSDK KFMLDMPFGK KCMESGREQL FPETPTSSLP LAEARDMPNH ADTQGLAGAW
     PHSKAPDAQG RLVQAQSSID ADINSQNLER ALVTPFKKDS EFTWDWQETS SKALKIKDLD
     FSDLCNEEDF DVLDTATIEN GSLHAPPPLP PGIGLMAEGG PMALPPPPPP LGCPPPPPPV
     PGCPLPPPPP APLGSSIPNG HSPPKKKKTV KLFWKELKQP DNCTGAGKFG QATVWSSLQR
     VEIDAAKLEH LFESRAKEVP SSKKAVDAKK TVVIVLDPKR SNAINIGLTV LPPAHIIKTA
     ILNFDEFAVN KEGIEKILTM VPTDEEKQKI QEAQLANPEV PLGSAEQFLL TLSSISDLTA
     RLQLWAFKLD YESMEQEIAE PLFDLKLGME QLAKNYTFKC ILATLLATGN FLNGSQSKGF
     DLSYLEKVSE VKDTVHRQSL LHHLCQMVVE KFPETTNLYS EIAALTRSAK VDFDELADSL
     VQLERRCKAS WDSLKVITKH EYKSVLKSKL TDFLKESTQK IIILKVVHRR VLNRFHSFLL
     YLGYPTNAVR DVKVTRFCKT LREFALEYRT CWERVLQQQK KRAAHRERNK TRGRLITETE
     KFSSIASSTE TSSPVPAVST SPEQQAEAGH ESMKSMLISS TETPARRSRA SRGVGQSSPS
     SGSPAQEDTS SSPDDASDEI MDRLVKSVTH NPNPRPGAAK ERKRSRVNRK SLRRTLKSDL
     SEDVVKALGL ARTPGVDV
//