ID A0A3Q0H0U9_ALLSI Unreviewed; 235 AA.
AC A0A3Q0H0U9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=LOC102371910 {ECO:0000313|RefSeq:XP_025064018.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025064018.1};
RN [1] {ECO:0000313|RefSeq:XP_025064018.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|RuleBase:RU361155}.
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DR RefSeq; XP_025064018.1; XM_025208233.1.
DR AlphaFoldDB; A0A3Q0H0U9; -.
DR KEGG; asn:102371910; -.
DR InParanoid; A0A3Q0H0U9; -.
DR OrthoDB; 10019at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF11; HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 4; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637359-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transferase {ECO:0000256|RuleBase:RU361155}.
FT DOMAIN 55..212
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT BINDING 67
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 75
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 192..196
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT DISULFID 175..187
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-3"
SQ SEQUENCE 235 AA; 26890 MW; 6A739D92270E7B3B CRC64;
MGEPGLVSVL AMPQRHRCTE AGDRSVMPKT LEGQITMEKT PSYFVTNEAP KRIHSMAKDT
KLIVVVRNPV TRAISDYTQT LSKKPDIPTF EVLAFKNRTL GLIDASWSAI RIGIYALHLE
NWLQYFPLSQ ILFVSGERLI IDPAGEMAKV QDFLGLKRLV TEKHFYFNKT KGFPCLKKPE
DGSPPRCLGK SKGRTHPKID PDVIHRLRKF YKPFNVMFYQ MTGQDFQWEQ EGSDK
//
