ID A0A3Q0H819_ALLSI Unreviewed; 1000 AA.
AC A0A3Q0H819;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger protein 135-like isoform X1 {ECO:0000313|RefSeq:XP_025068201.1, ECO:0000313|RefSeq:XP_025068202.1};
GN Name=LOC106722584 {ECO:0000313|RefSeq:XP_025068201.1,
GN ECO:0000313|RefSeq:XP_025068202.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025068201.1};
RN [1] {ECO:0000313|RefSeq:XP_025068201.1, ECO:0000313|RefSeq:XP_025068202.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025068201.1; XM_025212416.1.
DR RefSeq; XP_025068202.1; XM_025212417.1.
DR KEGG; asn:106722584; -.
DR OrthoDB; 4328541at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 17.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR003655; aKRAB.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16515:SF52; HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9; 1.
DR PANTHER; PTHR16515; PR DOMAIN ZINC FINGER PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 17.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS50806; KRAB_RELATED; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 17.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 109..188
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT DOMAIN 319..383
FT /note="KRAB-related"
FT /evidence="ECO:0000259|PROSITE:PS50806"
FT DOMAIN 322..394
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 529..556
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 557..584
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 585..612
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 613..640
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 639..666
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 667..694
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 695..722
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 723..750
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 751..778
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 778..805
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 806..833
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 833..860
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 861..888
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 889..916
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 917..944
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 945..972
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 973..1000
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 232..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1000 AA; 112774 MW; DC8BFF82EC3A564C CRC64;
MAAALEPVAA VGLPSAVLVQ GEVKMEERDT AGLQAGAEGT GQVHRVLQAG AGELSPRWSA
PQQVKQQLQE EPVQCQEIQG EEAMQPVQPP PGATQLAPGD VLPTPETWRQ HFRSLRYQEG
EGPRGVCSRL RELCQRWLEP QRRSKEQILE LVVLEQFLAI LPREMQSWQW GHGVETCAEA
VALAEGFHLG QAENERLQVT VSVNVEEVSS GTMRPTGDFQ GLVDSCLEHL LEEAGQRETP
GTRDKPALVP KEDEPPPHQE SGAGTLDRAD QQPPEEEPVN WELQRTSPGR LGERGSLTPD
LGQVQKRQGR PPKQGESTEL GEVFEAVAVY FTRKEWELLG DEDKVLYRDQ MLRNFHALVS
LGYGGPTPNL ICRVQQGELE LWVCEDEDHG EISRSEDLSP GGACLLGRAE EQRPEEGPAN
VEPPQTSPGT LGEMGSLRPE KDQWQKGQEN IAVNQVPSPM GCEIGEETTA RKSPEFRGQF
VELRGLKSLD HSKIHSGELP HRFIKCAKSF VCSPDLVKHQ HVHREKRRYQ CITCGKTFTQ
FFSLAQHRHV HLGRKTHRCT KCRKNFICWQ DLSRHRCVQR EEQPHHCTKY GKRFRRPSDL
AQHRCLHTRE KTHQYSPCGA IFIRSSILAK HQLIHTGQTP CSDSGKSFTR PSHLARHHLV
HTGENLYQCP ECGKSFTQSS RLAQHQRIHT GEKTLGCPEC GKSFSRSSSL ARHQLIHTGE
KRHQCSVCGK SFTQSSTLVQ HQRVHTGEKP HRCSECGKSF TQSSSLGRHQ DLHREKAHQC
LVCGKSFTHS CHLARHQRIH TGEKPYRCSG CGKSFILSSS LARHQRRQAG KADQCLVCGE
RFTLSCHLAE HQRIHIRKPS HQCSECGKSF TESSSLAQHQ RIHRVERPHQ CSECGKRFTQ
ASHLARHQLT HTAEKPHRCS ECGKSFTQPY SLSQHQRIHT AEKPYQCSEC GKGFTQSSHL
ARHQRIHTAE KPYQCSECGR SFTQSSHLAR HQRIHSREHP
//
