ID A0A3Q0H9C8_ALLSI Unreviewed; 138 AA.
AC A0A3Q0H9C8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Insulin-like peptide INSL5 {ECO:0000313|RefSeq:XP_025068666.1};
GN Name=INSL5 {ECO:0000313|RefSeq:XP_025068666.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025068666.1};
RN [1] {ECO:0000313|RefSeq:XP_025068666.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Heterodimer of a B chain and an A chain linked by two
CC disulfide bonds. {ECO:0000256|ARBA:ARBA00011207}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU000406}.
CC -!- SIMILARITY: Belongs to the insulin family.
CC {ECO:0000256|ARBA:ARBA00009034, ECO:0000256|RuleBase:RU000406}.
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DR RefSeq; XP_025068666.1; XM_025212881.1.
DR AlphaFoldDB; A0A3Q0H9C8; -.
DR STRING; 38654.A0A3Q0H9C8; -.
DR KEGG; asn:112551518; -.
DR InParanoid; A0A3Q0H9C8; -.
DR OrthoDB; 4255151at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR CDD; cd04365; IlGF_relaxin_like; 1.
DR InterPro; IPR016179; Insulin-like.
DR InterPro; IPR036438; Insulin-like_sf.
DR InterPro; IPR022353; Insulin_CS.
DR PANTHER; PTHR20968; ILGF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR20968:SF2; INSULIN-LIKE PEPTIDE INSL5; 1.
DR Pfam; PF00049; Insulin; 1.
DR SMART; SM00078; IlGF; 1.
DR SUPFAM; SSF56994; Insulin-like; 1.
DR PROSITE; PS00262; INSULIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Secreted {ECO:0000256|RuleBase:RU000406}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..138
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017945824"
FT DOMAIN 27..138
FT /note="Insulin-like"
FT /evidence="ECO:0000259|SMART:SM00078"
FT REGION 62..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 138 AA; 15193 MW; 7AE4C740A7F64C0A CRC64;
MKGTILALVL FSALVAASEA KGEGSFMKLC GRDFVRAVVF TCGGSRWKRH LSDYPHVSER
EKHLHLPHGS NDYPESLGYG DQAPESLNEE IPNTKTESER DLTVVRQMSM AEKREVAALL
TTSCCSIGCT ERDISSLC
//
