ID   A0A3Q0H9G5_ALLSI        Unreviewed;       520 AA.
AC   A0A3Q0H9G5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Islet cell autoantigen 1 isoform X4 {ECO:0000313|RefSeq:XP_025068701.1};
GN   Name=ICA1 {ECO:0000313|RefSeq:XP_025068701.1};
OS   Alligator sinensis (Chinese alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025068701.1};
RN   [1] {ECO:0000313|RefSeq:XP_025068701.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025068701.1; XM_025212916.1.
DR   AlphaFoldDB; A0A3Q0H9G5; -.
DR   Proteomes; UP000189705; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR   CDD; cd07661; BAR_ICA69; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR010504; AH_dom.
DR   InterPro; IPR024114; Islet_autoAg_Ica1/Ica1-like.
DR   InterPro; IPR006723; Islet_autoAg_Ica1_C.
DR   PANTHER; PTHR10164; ISLET CELL AUTOANTIGEN 1; 1.
DR   PANTHER; PTHR10164:SF3; ISLET CELL AUTOANTIGEN 1; 1.
DR   Pfam; PF06456; Arfaptin; 1.
DR   Pfam; PF04629; ICA69; 1.
DR   SMART; SM01015; Arfaptin; 1.
DR   SMART; SM01237; ICA69; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS50870; AH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189705}.
FT   DOMAIN          51..254
FT                   /note="AH"
FT                   /evidence="ECO:0000259|PROSITE:PS50870"
FT   REGION          401..432
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          449..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..418
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        449..480
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  59247 MW;  B3F77F0E9E50AF85 CRC64;
     MDGHSYSREF YDRYAQSQEK SVVNKMQQKY WKTKQTLIKV TGKKEDEHVV ASDADLDAKL
     ELFHSIQRTC MELLKAIELY QKRICFLSQE ENELGKFLRS QGSQDKTRAG KMMQATGKAL
     CFSSQQRLAL RTPLSRLYQE VETFRYRAIS DTWLTVNRME QYRTEYRGAL LWMKDVSQEL
     DPDLYKQMEK FRKVQAQVRH TKLNFDKLKT DVCQKVDLLG ASRCNLLSHV LTTYQTTLLH
     FWEKTSHTMA AIHESFKGYQ PYEFTMLKSL QDPVNKLTER TEKEDLQTES TKSVDDQQSQ
     LISLYEENHS KEPSYSAEDS KDILTTLGEN FNHRENSGAI DDLLDLKPEE NAWEYRSKGK
     ASNSPELDSG EKDDMVLLNE ILNATSLDEG EFSKEWTAVF GQDPLTDPTT NSSVGEMETA
     PSAAAAPSGF LPSQLLDQNM NDLQSSLHGW AANSVSPPSI PQPAQKSNSL NVNTNKTPVK
     EPAKNPKDLT AWFSLFADLD PLSNPDAVGK TDKEHELLNA
//