ID A0A3Q0HCT3_ALLSI Unreviewed; 1326 AA.
AC A0A3Q0HCT3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Zinc finger protein 521 isoform X7 {ECO:0000313|RefSeq:XP_025069804.1};
GN Name=ZNF521 {ECO:0000313|RefSeq:XP_025069804.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025069804.1};
RN [1] {ECO:0000313|RefSeq:XP_025069804.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025069804.1; XM_025214019.1.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406:SF8; C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF13912; zf-C2H2_6; 6.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 27.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 9.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 23.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 21.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 138..165
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 166..193
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 194..221
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 222..249
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 266..294
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 301..329
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 330..357
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 457..485
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 497..525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 533..561
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 654..676
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 684..706
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 714..738
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 742..770
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 772..800
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 803..830
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 829..852
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 906..933
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 950..977
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 979..1006
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1158..1186
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 883..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1326 AA; 149905 MW; E6A64E3AD756A907 CRC64;
MSRRKQAKPR SLKVEENETE DQQGGVGQTA AQTDPNCKLE DKAEDGEVID CKKRPDEGEE
LEEEAVHSCD SCLQVFESLS DITEHKINQC QLTDGVDVED DPTCSWPASS PSSKDQTSPS
HGEGCDFGEE EGGPGLPYPC QFCDKSFSRL SYLKHHEQSH SDKLPFKCTY CSRLFKHKRS
RDRHIKLHTG DKKYHCSECD AAFSRSDHLK IHLKTHTSNK PYKCAICRRG FLSSSSLHGH
MQVHERNKDG SQSASRMEDW KMKDTQKCSQ CEEGFDFPED LQKHIAECHP ECSPNEDRSA
LQCVYCHELF VEETSLVNHM EQAHNGEKKN SCSICSENFH TVEELYSHMD SHQQPESCNH
SNSPSLVTVG YTSVSSTTPD SNLSVDSSTM VEAAPPITKG RGRKRAAQQV PDITGPSSKQ
AKVTYSCIYC NKQLFSSLAV LQIHLKTMHL DKPEQAHICQ YCLEVLPSLY NLNEHLKQVH
EAPDPALIVS TMPAMVYQCN FCSEVFNDLN TLQEHIRCSH GFANPAAKDS NAFFCPHCYM
GFLTDSSLEE HIRQVHCDLS SSRFGSPVLG TPKDPVVEVY SCSYCTNSPI FNSVLKLNKH
IKENHKNIPL ALNYIHNGKK SRAMSPLSPV TIEQTSLKMM QAVGGAPPRP AGEYICNQCG
AKYTSLDGFQ THLKTHLDTV LPKLTCPQCN KEFPNQESLL KHVTIHFMIT STYYICESCD
KQFTSVDDLQ KHLLDMHTFV FFRCTLCQEV FDSKVSIQLH LAVKHSNEKK VYRCTSCNWD
FRNETDLQLH VKHNHLENQG KVHKCIFCGE SFGTEVELQC HITTHSKKYN CKFCSKAFHA
IILLEKHLRE KHCVFETKTP NCGTNGASEQ VQKEEVELQT LLTNSQESHN SHDGSEEDVD
TSEPMYGCDI CGAAYTMETL LQNHQLRDHN IRPGESAIVK KKAELIKGNY KCNVCSRTFF
SENGLREHMQ THLGPVKHYM CPICGERFPS LLTLTEHKVT HSKSLDTGNC RICKMPLQSE
EEFLEHCQMH PDLRNSLTGF RCVVCMQTVT STLELKIHGT FHMQKTGNGS AVQTTGRAQH
LQKLYKCASC LKEFRSKQDL VKLDINGLPY GLCASCVNLS KSGSPSVNIP SSSNRQGLGQ
NENLSSIENK SKAGGLKTRC SSCNVKFESE SELQNHIQSI HRELVPDSNS TQLKTPQVSP
MPRISPSQSE EKKTYQCIKC QMVFYNEWDI QVHVANHMIG EKMRRKVKMR EDVEEEMKEE
TGSETGSFNN MTLSHRSQLH RSLMLLFLQF LEKILQELLW CKVLEGRYTC TSTSSRGPRR
VGITSR
//
