ID A0A3Q0HDV9_ALLSI Unreviewed; 635 AA.
AC A0A3Q0HDV9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Major facilitator superfamily domain-containing protein 6-like {ECO:0000313|RefSeq:XP_025068673.1};
GN Name=MFSD6L {ECO:0000313|RefSeq:XP_025068673.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025068673.1};
RN [1] {ECO:0000313|RefSeq:XP_025068673.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC {ECO:0000256|ARBA:ARBA00005241}.
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DR RefSeq; XP_025068673.1; XM_025212888.1.
DR AlphaFoldDB; A0A3Q0HDV9; -.
DR STRING; 38654.A0A3Q0HDV9; -.
DR KEGG; asn:102376723; -.
DR InParanoid; A0A3Q0HDV9; -.
DR OrthoDB; 5406687at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17479; MFS_MFSD6L; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR16172:SF22; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE; 1.
DR PANTHER; PTHR16172; UNCHARACTERIZED; 1.
DR Pfam; PF12832; MFS_1_like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..571
FT /note="Major facilitator superfamily associated"
FT /evidence="ECO:0000259|Pfam:PF12832"
FT REGION 165..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_025068673.1"
SQ SEQUENCE 635 AA; 69292 MW; 29655F4335613A5A CRC64;
GRQHVAEATS TNQQWDVHKA LAVAGVFHFL HGAGNACVAP FLSLYCRQLG LPAPLVGIVM
GIKHLVSCLW APLASYLAKS RGKRKVLIAA SLLGSVGAGL LLTLVPPLSQ EALYRYCNVS
HASPGATADV GTSNTSGSAA AVGTRVRPAV RKAAFQELIG FTDPLEEKNG RAGKDDKSAD
PRVSGAPGVT ASVQVKQVAQ ELHTPPSGET RFNQPEQGTS SLGSRFLKVN DNPEENFPMS
GSSELSLFQT NPRPVVETPY VFENLSGHWE DAQDVNLELL PVNFLDREHQ VFLMVLGAVV
FWELLAAPLE WTVDDSLYEY LDFVDATDRY GNLWIWSYLG ASGGACSIAI LVDQLNCFLN
TEVSRLAVHF YGYALLITLT LLVSIFFPIH VSRKTEHVNK TVKALNLIGS DGRTILSAVT
VFLTGVIGST VQNFLFWQMQ DQGSTELYMG LSVAIGLIAE ILLHFCKSRL LRTLSSSGTV
ALSLSCLALQ LLYYSFLWNA WAVLPIQILS AFSNGSLWWA VNMMVDDVAT PGTERALHVV
LQGLSYGCGA SLGSFTGGFV VSNFGLAVLY RACCISLILW LILFLIVQSK LPRQKKINYS
RLLAADPSDV SDSDEERERD WLVKAMKDEH FSRNW
//
