ID A0A3Q0HPF8_ALLSI Unreviewed; 1008 AA.
AC A0A3Q0HPF8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Teashirt homolog 3 {ECO:0000313|RefSeq:XP_025072393.1};
GN Name=TSHZ3 {ECO:0000313|RefSeq:XP_025072393.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|Proteomes:UP000189705, ECO:0000313|RefSeq:XP_025072393.1};
RN [1] {ECO:0000313|RefSeq:XP_025072393.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the teashirt C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00007158}.
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DR RefSeq; XP_025072393.1; XM_025216608.1.
DR AlphaFoldDB; A0A3Q0HPF8; -.
DR STRING; 38654.A0A3Q0HPF8; -.
DR KEGG; asn:102377618; -.
DR InParanoid; A0A3Q0HPF8; -.
DR OrthoDB; 5407068at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR027008; Teashirt_fam.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR12487:SF5; TEASHIRT HOMOLOG 3; 1.
DR PANTHER; PTHR12487; TEASHIRT-RELATED; 1.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 204..233
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 816..887
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 968..996
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DNA_BIND 818..888
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..817
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 110854 MW; C962AFBD11BFFA71 CRC64;
MDSESHISET SDRMADFESS SIKNEEESKE VSIPLEDSTV SDSLEQMKAV YNNFLSNSYW
SNLNLNLHQP TSEKNNGSSS SSSSSSSSCG SGSFDWHQTA MAKTLQQVSQ SRILPEPSLF
STVQLYRQSS KLYGSIFTGA SKFRCKDCSA AYDTLVELTV HMNETGHYRD DNHETDNNNP
KRWSKPRKRS LLEMEGKEDA QKVLKCMYCG HSFESLQDLS VHMIKTKHYQ KVPLKEPVTP
VAAKIIPATR KKASLELELP SSPDSTGGTP KATISDTNDA LQKNSNPYIT PNNRYGHQNG
ASYAWHFEAR KSQILKCMEC GSSHDTLQEL TAHMMVTGHF IKVTNSAMKK GKPIIEAPAT
PTITSLVDEK VQSVPLAATT FTSPSNTPSS VSPKLNVEVK KEVDKERGIA DDKMKDKEKS
SEEEEKYDIS SKYHYLTEND LEESPKGGLD ILKSLENTVT SAINKAQNGT PSWGGYPSIH
AAYQLPNMMK LSLGSSGKST PLKPVFGNNE IVSPTKNQPL VSPPSSQTSP VPKTNFHAME
ELVKKVTEKV AKVEEKMKEP EGKLSPMKRA TPSPCSSEVS EPLKMDAPSD SGFKSQQSSP
VPQRDSCKDS PTVEPVENGK EPVKSIVSTL SSSTAIITDH PPEQPFVNPL SALQSVMNIH
LGKAAKPSLP ALDPMSMLFK MSNSLAEKAA VATPPLQSKK TDHLDRYFYH VNNDQPIDLT
KGKSDKSCSL GSALLSSTST SSASSSSTVT TAKTSAVVSF MSNSPLRENA LSDISDMLKN
LTESHTSKSS TPSSISEKSD IDGTTIEEPE ESTPAQKRKG RQSNWNPQHL LILQAQFAAS
LRQTSEGKYI MSDLSPQERM HISRFTGLSM TTISHWLANV KYQLRRTGGT KFLKNLDTGH
PVFFCNDCAS QIRTPSTYIS HLESHLGFRL RDLSKLSNEQ INNQIAQAKS PSEKLVTSSP
EEEIGTSYQC KLCNRTFASK HAVKLHLSKT HGKSPEDHLL YVSELEKQ
//
