ID A0A3Q0IKD8_DIACI Unreviewed; 1014 AA.
AC A0A3Q0IKD8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=DNA repair protein complementing XP-C cells homolog {ECO:0000313|RefSeq:XP_026676736.1};
GN Name=LOC103505828 {ECO:0000313|RefSeq:XP_026676736.1};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_026676736.1};
RN [1] {ECO:0000313|RefSeq:XP_026676736.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
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DR RefSeq; XP_026676736.1; XM_026820935.1.
DR AlphaFoldDB; A0A3Q0IKD8; -.
DR STRING; 121845.A0A3Q0IKD8; -.
DR PaxDb; 121845-A0A3Q0IKD8; -.
DR KEGG; dci:103505828; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 2.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR018026; DNA_repair_Rad4-like.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR NCBIfam; TIGR00605; rad4; 1.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169}.
FT DOMAIN 718..770
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 772..828
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 835..909
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..527
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..600
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 116099 MW; 760022B701F8FAF5 CRC64;
METRRSSRRL QNRSTEFTKP VMKRKSESPE IKSKCETKVS SPKKPKVETK NRPSETIGSI
FDNDAPIDSI LDKIRRDSIE KCVAGAPNVN LSSDSESDDE SSDENFEKFN KSVKTDNDDV
SKHVENEPPV VETSEYFDFS KILSKQNSFQ SLLSQSKQPG KQGKETSTVP DFVDESPLEC
NNKNNLKGNV EINKCRSNKN ELPRKGKSSI RSSSRNKSSP HTSKTVETSR RSNEGSSKQK
SSTKVKKDEE LNVKDLLALG EGVDASQLEN YEEESPKESD YKIPDKVEIT LDLPNAGKKK
KKAGFDLEAA LKRRLNLVKK ENQVFVHKVH LLCLLSHGFH LNKSLNCENL IGVALSLIPS
KHCYPPKHAD ISYLENFISW FCKKISIEDP TNVKFNVDCT TITNHLILCF NKHKANNKID
LILMFITVMR SLGMKCRLMI NLQPEPLKPS SDNLLPLNSK PSSESPSKSK SEPKPKKETK
KNLRFENKKE KKSEKSKYFS SDSNPSPSKY FKGNEKDLSK KLPIPKSGKG KPDLNSQPSC
SKSKKHIESD DDFIMSDGDS DDDFVTPKKS RKTPSKSSTK ISPSSKKDGK INRKVLSTDE
SEVESTSTKP NKKQGLDIWC EVFLEAEEKW ISVDIVNKRY HCVEKLYAAA THPVSYVLAW
NNNNTVKDLT KRYAPQWLTM TQKLRVDSAW WKKTLKPYVP PKTVWEREED EELERHLKDQ
PLPLSLSEYK NHPLYVLPKD LLKFQAIHPP DLEPVGYFRG EKVYPRSAVK ELHTRETWLK
EARVVRLAEK PYKIVKARVK KDKFGFLPTE EKKSELFGIW QTEDYIPPVA QNGIVPRNSF
GNVDLFLECM LPIGTVHLQL PQLQRIARKL NIDCAPAMVG FEPCRFGSRP VMDGWVVCEE
FRDVLLDAWN QEYDEKTKAE NEKRRKRAKA NWRKLVRCLR VKKRLELRYQ FNLESDKERP
SSSKDVNVSR LDHGIPCSTG GGHHSMYMWF IKTSMQDILL SSLLCNQVWK LCFQ
//
