ID A0A3Q0IKV5_DIACI Unreviewed; 373 AA.
AC A0A3Q0IKV5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Metallophosphoesterase 1 isoform X2 {ECO:0000313|RefSeq:XP_026676802.1};
GN Name=LOC103505733 {ECO:0000313|RefSeq:XP_026676802.1};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_026676802.1};
RN [1] {ECO:0000313|RefSeq:XP_026676802.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. MPPE1
CC family. {ECO:0000256|ARBA:ARBA00008895}.
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DR RefSeq; XP_026676802.1; XM_026821001.1.
DR AlphaFoldDB; A0A3Q0IKV5; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR033308; PGAP5/Cdc1/Ted1.
DR PANTHER; PTHR13315; METALLO PHOSPHOESTERASE RELATED; 1.
DR PANTHER; PTHR13315:SF0; METALLOPHOSPHOESTERASE 1; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..287
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 373 AA; 43697 MW; 8255D1D4411FE5F9 CRC64;
MRLRYWHLCQ PLLVKVCLFL IGVFIFCEHF VYQLVLWQCN WPASPESINN IKAIFIADTH
LLGPFRGHWF DKLRREWQMY KTFQTAVALH QPEHIFVLGD LLDEGQYVGG EDFDNYVRRF
YSLFSTPDGT ELHVVPGNHD MGFHYRLHPY LNDRFSRAFN SSMVKLLSIK GSYFVLINSM
ALEGDGCFLC KPAQDRISLI SAKLKCSRKD RECPKSMKLG SYSQPIILQH FPLYRESDEE
CSGPDSAPDI EKRKKFRQRW ECISKESTDM LLDYLNPRLV IDGHTHNGCH KYHAYGKVHE
YTVPSFSWRN KNNPSFLMGI ISPDHFNISK CYMPEETTVL LIYAVSIILV IIYSVYKIKS
RTIYIRKYSS HMK
//
