ID A0A3Q0J5X5_DIACI Unreviewed; 489 AA.
AC A0A3Q0J5X5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN Name=LOC103512999 {ECO:0000313|RefSeq:XP_026682120.1};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_026682120.1};
RN [1] {ECO:0000313|RefSeq:XP_026682120.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361189}.
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DR RefSeq; XP_026682120.1; XM_026826319.1.
DR AlphaFoldDB; A0A3Q0J5X5; -.
DR STRING; 121845.A0A3Q0J5X5; -.
DR PaxDb; 121845-A0A3Q0J5X5; -.
DR KEGG; dci:103512999; -.
DR OrthoDB; 1967517at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 3.
PE 3: Inferred from homology;
KW Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 246..271
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
SQ SEQUENCE 489 AA; 55855 MW; CE0C7AB03AD7A7F3 CRC64;
MILLLRQNNA GPVQLGFVAG VALRERMPAF ERMLWRACRG NVFLRQAEIE TPLEDINSGD
PVYKSVFIIF FQGDQLKTRV MKICEGFRAT LYPCPEAPTD RREMSMGVTT RIEDLNTVIG
ETQDHRHRVL VAAAKNIKNW FIKVRKIKAI YHTLNFFNLD VTQKCLIAEC WVPVLDIDAI
QLALRRGTDR SGSSVPPILN RMDTFEDPPT YNRTNKFTKA FQALIDAYGV SSYREMNPTP
YTIITFPFLF AVMFGDLGHG AIMFLFAAWM VMKEKPLMTL KTDNEIWKIF FGGRYIILLM
GLFSMYTGLI YNDVFSKSLN LFGSNWKNNY NSSTLASNKD LQMDPKDDYI QYPYPFGLDP
IWQLSDGSSV PPILNRMDTF EDPPTYNRTN KFTKAFQALI DAYGDRSGSS VPPILNRMDT
FEDPPTYNRT NKFTKAFQAL IDAYGVSSYR EMNPSKVEFQ SKFYSGLGYA FQPFSFEIIL
ALAAASGDE
//
