ID   A0A3Q0J9Q3_DIACI        Unreviewed;      1682 AA.
AC   A0A3Q0J9Q3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE            EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN   Name=LOC103517157 {ECO:0000313|RefSeq:XP_026685161.1};
OS   Diaphorina citri (Asian citrus psyllid).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC   Diaphorininae; Diaphorina.
OX   NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_026685161.1};
RN   [1] {ECO:0000313|RefSeq:XP_026685161.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type III PI4K
CC       subfamily. {ECO:0000256|ARBA:ARBA00006209}.
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DR   RefSeq; XP_026685161.1; XM_026829360.1.
DR   STRING; 121845.A0A3Q0J9Q3; -.
DR   PaxDb; 121845-A0A3Q0J9Q3; -.
DR   KEGG; dci:103517157; -.
DR   OrthoDB; 147843at2759; -.
DR   Proteomes; UP000079169; Unplaced.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd05167; PI4Kc_III_alpha; 1.
DR   Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR   InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR   InterPro; IPR018936; PI3/4_kinase_CS.
DR   InterPro; IPR045495; PI4K_N.
DR   InterPro; IPR015433; PI_Kinase.
DR   PANTHER; PTHR10048:SF15; PHOSPHATIDYLINOSITOL 4-KINASE ALPHA; 1.
DR   PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
DR   Pfam; PF19274; PI4K_N; 4.
DR   SMART; SM00146; PI3Kc; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR   PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR   PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079169};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1402..1666
FT                   /note="PI3K/PI4K catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50290"
SQ   SEQUENCE   1682 AA;  189365 MW;  87A700D697CD6408 CRC64;
     MDNKNFFKKT VLHLARSLAA IKNVSWEKVK VLYDYCPQVS DSKSIVLDNR AQHAVIALGI
     YVLESDLCHV DKILDYLLKL LVTLPDVQWK DEVSKNSNQR IPTSEKFSFC LNTLLSDITF
     KYEECREQII STQIKVLTGL IEYCQNALSV LSLAKQLLQP DLLTYLDAQA SYVSSSGSIA
     MFPYRSFSET LNLVMVTLLR ELLQYQINYF LISPVHLCQN IVPVLIGLAR SMGRFPIQEP
     PLLTRIFPKP KPPCISPVAT GGAGGAPGQQ DKKKTFSTFR PIMPRSLSAS LNMTAVDILT
     LTSLDPMLDV RASHKLDVRE RFETNSSFDP STHFFVKYGS SFNQYPYTHL TRTSNDLHLS
     VTQLQVTDTT FHWPNYLDST LIQCNTIVML GHIAVSLKDT PKTTDTIVQF FQQRFCRVPS
     AVDILIVDQL GCIVIAKCEP HIYEEVMRMF ALVTVDASNA AYNTERSLAS QYRHVSRAVI
     NALANIAANL QGENEMHELL GRLLELFVQL GLEGKRASDK APAANKASSS AGNLGMLIPV
     IAVLVRRLPA IRSPKPRLHK LFRDFWLYCV LMGFTCESGL WPSEWTEGVK EIAAKSPYYV
     SQTSSRSEMR ELQYSAAVRN DSVSLPQLQE LKSQILQLLD HPPPDVVTSI QKLSFAQSTY
     LLSVYWLETL RVQNSPQPSL HPIFEYLLDQ SIQKDKSGIW QCISSVGQRV FTLFLDVMTH
     KSRDEAREAE LESHAQFLLV HFNHINKQIR RLADKWLSGL VDKFPHLLWN CKVLWTMLDI
     LQVLAYSLEL DPNEETPTLT IPGLPYTIPL TDTLDARETI VNDFSARCIG MLAGEGEEAV
     LERVLEGVWS ACRGSDNNAH HQALWTATAL LISMQGCPRQ LLAAVNCIYI FWLCQVAGML
     AGEGEEAVLE RVLEGVWSAC RGSDNNAHHQ ALWTATALLI SMQGCPRQLL AAVSWSQVEL
     FTEEAMRTAV DCWQWIATAK PELELTLLQE MVAAWQYTVD KKMGLFSAVV EQVSPLAAYE
     GCVLAPQAPF IRPHDIWIKC LCSAALGPRF RLLQCGLSLL QGDVLPRSLS KNVLRERIYC
     ACLDVFTVAP QCPTQRGSEL RDDITALVKF FQTMHSDKKY LMASVVGGKI QRVSVSGTGG
     RSKQRSSNHD LFVKDYIKKR NLILDLLAVR IEFLLTWHNP SGRPELSVTG EDIISAWKSK
     PVSDKTLIEL TRLAWDISPA LAVHLPQTLK NADAIVREVT RLVRLNPPSV MSLPVALQYL
     VTTDTILIYT LINDMTEKDP ILYDTLDSLV QALVASFSGP AKAFYEREFE FFAQITDISG
     KIRPFPKGAE RKRACLEELS KIKVRPGCYL PSNPEAVVLD IDYNSGTPMQ SAAKAPYLAR
     FRVKRCGINE LEQMAMAICE RDDDEEHDHQ LVRANSKDKI METWQAAIFK VGDDVRQDML
     ALQVISIFKN VFQQVGLDLY LFPYRVVATS PGCGVIECVP DAKSRDQLGR QTDIGMYEYF
     IKTYGDETSK EFQNARRNFV RSMAAYSVIG FLLQIKDRHN GNIMLDKAGH IIHIDFGFMF
     ESSPGGNLGF EPDIKLTDEM VMVMGGKIEA APFRWFMELC VQAFLAMRPY QESIISLVSL
     MLDTGLPCFR GQTIKLLRAR FAPQATDKEA AAFMIGVIRN SFLNFRTRAY DYLQYYQNQI
     PC
//