ID A0A3Q0JJX3_DIACI Unreviewed; 1190 AA.
AC A0A3Q0JJX3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=LOC103520598 {ECO:0000313|RefSeq:XP_026687448.1};
OS Diaphorina citri (Asian citrus psyllid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Psylloidea; Psyllidae;
OC Diaphorininae; Diaphorina.
OX NCBI_TaxID=121845 {ECO:0000313|Proteomes:UP000079169, ECO:0000313|RefSeq:XP_026687448.1};
RN [1] {ECO:0000313|RefSeq:XP_026687448.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
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DR RefSeq; XP_026687448.1; XM_026831647.1.
DR AlphaFoldDB; A0A3Q0JJX3; -.
DR STRING; 121845.A0A3Q0JJX3; -.
DR PaxDb; 121845-A0A3Q0JJX3; -.
DR KEGG; dci:103520598; -.
DR OrthoDB; 5490433at2759; -.
DR Proteomes; UP000079169; Unplaced.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF99; ATP-DEPENDENT RNA HELICASE DHX37-RELATED; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|RefSeq:XP_026687448.1};
KW Helicase {ECO:0000313|RefSeq:XP_026687448.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_026687448.1};
KW Nucleotide-binding {ECO:0000313|RefSeq:XP_026687448.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000079169}.
FT DOMAIN 302..458
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 129..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 526..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..221
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..543
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1190 AA; 133750 MW; 20F144856A6A2C5A CRC64;
MKNKKGHNWK ARQVVEATVI ENPSQKVSVD FETKTDSYDA ANPLVLPSKK RQTKIKKTNI
QVKKLLSKTQ RKKLEKIVEK KKKKENRAAL FETLAKVQAS EEVLNKLTSI SDVQTKGLKR
LKDEGDQYMK QVAEKEEGDP AVSSIAGSAK RRRLLLGLSN ESKRPKSNDP SVVGFQSSSD
EDSTESEEEG EEEEEEGQDE KDENPSEVEE VQEDVEEKET NETGDQLDKN FAELVDNDDD
DIIIEKELKK KEMMDTKPVK SEPETKPKTP SKPAVFIPVY RKPAIQEARM KLPILAEEQT
IMETINESNI IIVAGETGSG KTTQIPQFLY EAGYTSKRMI GVTEPRRVAA ISMSNNGLSS
EHVTVLSWVS NLSAETAGCN NHVSATLRIS DFTENTRLFK TPAHERSVYT DILIGLLSRI
VPLRLKRGDP LKLIIMSATL RISDFTENTR LFKTPPPVIQ VDARQFPVTI HFNKKTPTDY
LQEAFIKACK IHAKLPDGGI LIFVTGQKEV CSLVRKLKHT FPYKKSTEKA KDENENKTDE
NEANEEGNDS DDDLSMKTII NRMKRNKKKE ITLPDINLDN YGPKLQLDIA DLMVGFRLNP
VALTCDIKSM FRCVQVDKAD RMYQHILWRP DPSQNPMEME IKTVVFGLPS SPYQANRVIQ
QLASDEGDKY PQAAQTLREE IYVDDIVSGA ASVDEAKDLR NQLISLLEAG GFTLRDYDSI
DIIGFADASC LAFAAVVYLR IVPEIQRKPV DDLLLQMKAM SIHRVVNFPF PSAPDVIQLR
AGERRLALLG ALQPVLVKTT GKTKHMDEYC SKLTPLGEAM SLFPVSPRFA KMLCLSHQHS
LLPYTIAIVA ALSVQELLLS PDSNVTKIRT KWAGVNNSLL LGDLMVLLRA VGAAEKANVS
GNMEEFCIKH GLRLKAVVET RKLRIQLTNE LNMNIPDLEL CVDPDMAPPS DTQARLLRQI
ALSGMVDQVA RATSDEEKKA LGIPKKKPLY SIPEMEEGVY LHSGSVLRKT MPEWVVYEEI
FQTDDKMIMR GITAIEPEWL PVYAPSLCTF SSPLEHPTPR YIPTTKKLMC HVNATFGKSG
WPLPVVEIEM PKGLDRFKWF AVFLLDGSIC PKLSKYVTSL LSTPTTMVKS WASLQRRTEI
LLQALVQKNT DSVDILMDIW KSEPAYLRSE YLQWLPESAH NEVTASWPPV
//
