ID   A0A3Q0KCR8_SCHMA        Unreviewed;       454 AA.
AC   A0A3Q0KCR8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Putative gtp-binding protein hflx {ECO:0000313|WBParaSite:Smp_016550.2};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_016550.2};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of the
RT   human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN   [2] {ECO:0000313|WBParaSite:Smp_016550.2}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_016550.2};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q0KCR8; -.
DR   STRING; 6183.A0A3Q0KCR8; -.
DR   EnsemblMetazoa; Smp_016550.2; Smp_016550.2; Smp_016550.
DR   WBParaSite; Smp_016550.2; Smp_016550.2; Smp_016550.
DR   InParanoid; A0A3Q0KCR8; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   ExpressionAtlas; A0A3Q0KCR8; baseline.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.11060; GTPase HflX, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030394; G_HFLX_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR016496; GTPase_HflX.
DR   InterPro; IPR042108; GTPase_HflX_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10229:SF0; GTP-BINDING PROTEIN 6-RELATED; 1.
DR   PANTHER; PTHR10229; GTP-BINDING PROTEIN HFLX; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51705; G_HFLX; 1.
PE   4: Predicted;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854}.
FT   DOMAIN          280..402
FT                   /note="Hflx-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51705"
SQ   SEQUENCE   454 AA;  51341 MW;  7CD81160EA608566 CRC64;
     MFRNVGRLFR YFPDRRCSSL VDADSNKVYD ELLKKSYLLP ENGHDIVIIQ PHIKGALYKR
     INNKFPYLPK NDPNVDEAIA LVDSLGFWTT VGVIFCNIKA ANTNRGPFFS KGIWQNVSDS
     VIAYRDGKQS VQTADTLPNE ENNTFSEHIV KKRATAVLVN WPRLTTLQLA LMQQAWLIPV
     YDRYTLVVQL FSLRSRTPEA KLQAKLAEIG LLRARIPAFF ETPNMIKRLI DRSDFATKER
     LIQILNQTEA SLLNQLEKIS KQRIHHRRNH RRDMEKHHLP LVAVVGYTNA GKTSLIRYLS
     KSDKLTSSPE VFATLDITHH RSRLPILPNK TEENNMTSNQ LSSGNVSDGC CSSSIGLPGI
     QMLLLDTIGF MSDLPTNLLA AFRATLDECL DADLILHIVD VSQPEWQLQV NHVEELLCSI
     GVLVTKSTNS GHTSDSNTFE PPQVLKIGNK VDRM
//