ID A0A3Q0KJS3_SCHMA Unreviewed; 396 AA.
AC A0A3Q0KJS3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Actin-related protein 2 {ECO:0000313|WBParaSite:Smp_101290.1};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_101290.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_101290.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_101290.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells. {ECO:0000256|ARBA:ARBA00003520}.
CC -!- SIMILARITY: Belongs to the actin family. ARP2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010121}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q0KJS3; -.
DR STRING; 6183.A0A3Q0KJS3; -.
DR EnsemblMetazoa; Smp_101290.1; Smp_101290.1; Smp_101290.
DR WBParaSite; Smp_101290.1; Smp_101290.1; Smp_101290.
DR InParanoid; A0A3Q0KJS3; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR ExpressionAtlas; A0A3Q0KJS3; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF37; ACTIN-RELATED PROTEIN 2; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854}.
SQ SEQUENCE 396 AA; 44808 MW; E7B5BEF5E6DB8A0A CRC64;
MTVDADGNKI VVCDNGTGFV KCGYAGATFP EFIFPSLIGR PILRATSRVG NLEVQDLMVG
DEASELRQML ELSYPLENGI VRNWDDMIHL YDYIFGPKKM NIDPKHAKIL LTEPPLNPLR
NREKMVEVMF EKYGFNALFI AIQATLTLYA QGLMTGVVVD SGDGVTHICP VYDGLSLPHL
TRRLNVAGRD ITRYLIKLLL LRGYAFNQTA DFETIRQMKE KLCYVAYDVE QEQNLALDTT
VLVKKYTLPD GRVIKVGGEL FGAPEALFQP HLIDREGVGI SELLFNTIQA ADIDTRPGLY
KHIVLSGGST MYPGLPSRLE REIKQLYLQN VLKGDTERFA KFKMCIEAPP QRKHMVFIGG
SVLANIMKND RRTTWLTRAE YEEKGLKVLE RLNYYK
//
