ID   A0A3Q0KJZ6_SCHMA        Unreviewed;      1474 AA.
AC   A0A3Q0KJZ6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Cell polarity protein {ECO:0000313|WBParaSite:Smp_104030.2};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|WBParaSite:Smp_104030.2};
RN   [1] {ECO:0000313|WBParaSite:Smp_104030.2}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_104030.2};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q0KJZ6; -.
DR   STRING; 6183.A0A3Q0KJZ6; -.
DR   EnsemblMetazoa; Smp_104030.2; Smp_104030.2; Smp_104030.
DR   WBParaSite; Smp_104030.2; Smp_104030.2; Smp_104030.
DR   InParanoid; A0A3Q0KJZ6; -.
DR   ExpressionAtlas; A0A3Q0KJZ6; baseline and differential.
DR   CDD; cd00992; PDZ_signaling; 4.
DR   Gene3D; 2.30.42.10; -; 4.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR23119; DISCS LARGE; 1.
DR   PANTHER; PTHR23119:SF44; PROTEIN SCRIBBLE HOMOLOG; 1.
DR   Pfam; PF00560; LRR_1; 2.
DR   Pfam; PF13855; LRR_8; 3.
DR   Pfam; PF00595; PDZ; 4.
DR   SMART; SM00364; LRR_BAC; 10.
DR   SMART; SM00369; LRR_TYP; 14.
DR   SMART; SM00228; PDZ; 4.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF50156; PDZ domain-like; 4.
DR   PROSITE; PS51450; LRR; 4.
DR   PROSITE; PS50106; PDZ; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          920..1008
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          1052..1140
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          1212..1297
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          1304..1405
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          474..672
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          691..753
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        476..584
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        587..601
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        620..672
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        691..749
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1474 AA;  161229 MW;  0096D94EB81B1037 CRC64;
     MFKCLPIIGP CGRHTDHIDR RHSKLEQVPD DVIRNFRTLE ECRLDANQIK ELPKNFFRLK
     RIRLLTLSDN ELTRLPTGIG SFSNLVELDI SRNDISELPA SIRFCDSLQS LDVSNNPLQS
     LPAGFCQLRN LRVLCLNDIS IAELPEEIGS LQLLEKLELR DNCLKSIPDS FADLIHLEFL
     DLGANEFQEL SPVIGQLSQL SELWIDDNEL RSLPKELGNL GNLQQLDLSE NLISTLPESI
     SGLVSLSDLN LSQNSITHLP NGLGDLDKLI ILKLNQNRLL TVTPTIGNCS SLQELYLTEN
     FLSKLPSSIG NLVSMFHLNV DQNQLTELPS EIGQCTSLNI LSLRENNLHR LPDEIGNCTR
     LRVLDVSGNR LDRLPFSLSR CSLTALWLSQ NQSQPVITLQ RDVDPVTQEQ YLTCYLLPQD
     QLDSRVETDP TMSPSELDSF SASLNANMKT NHDLLDNISA EINHTYEPAD MHISIPQSDL
     SKNRSISPSK YESTKPSTSP SSTLNDHSAI TNDPNSLNNH HSVNSTTNPT KNLPYSNSSI
     NSPSNVNGNL DSSYTSPNHI NDLSTSSAHS SLSMPTSAST RVHFSGSVKP DEMDKSGSKG
     FPKTRHPRSC KKATDNHLIS GKDDSSQCRS ANFPSNTFRD GTGSASSSES LNDGSAPISP
     SESLNHDWNS PKPIDSNFNS SVYPNHIMKS NDGSSLVTND NLISTEPTAK PRNKSQNVTE
     IFGNKPTQPS NFLNEHPASK SSTEISRPKI PGDTTIRMAS VEDNSNAHSN RESPMKKFPD
     NLDVQGNLDE DAYSSGGEEI YVISRRVGFT DDVEDNEEKS NQKLIRRDTP HYTKRARIQS
     KTADGMDSEE AVLKILEKYR ASVSPNPDSN SIDFDGAVKR FASPFGGLSP PDIPLQSRDL
     HSPSSLHKQP VASCQQEQVV VHIHRQPNAG LGLSVAGGVG SIPFRGLDHG IFVSRLNPTG
     LAATSGLKLG DKLLEVNGVS LINVEHHVAV ATLRANTNDF RILVGRDIQM STKADNYKII
     PSMLSGTNLN MSTQSSRVTG SINTKEIPEF IHCTLQRDLN GLGFSIAGGQ GSLPPPLDNE
     AIYVSKITEG GAAHKQGQLR VGDQIISING VDIRNARHDE AISLLTSSND SVDLELLRYN
     PDINDNLGSL PKTSANGFIT SSILTVKRSN NPQDTTKATD LTDTDSHISE KCDSRVYLYS
     EKGIPVERIT VRNDGGPLGL AICGGSDISC LPFGNKEPGI FISKISLDGA ALNTGLRIGD
     RVLKVNGVDL RHATHDEAVQ ALIQPVKELQ LDVRRDPPPP GLRRITVTKR PGERYGLRVT
     GGLNTSDSNM ITNLGSHYSS LANDDGIFVT WVSPDGVIAR DGRLKPGDRL LEINGHWLMG
     VTLDEVLHIF WGSKSTLSCV VCDGPVEFAL QINKTNHSGN IEPSTYSPAM PFSIIRSTMP
     EIADASVDDN PTSNSQLDKV NSTHRLNLEA AVRH
//